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Biomimetic engineering design of biohybrid soft nanorobots to combat antimicrobial resistance and advance an integrated understanding of illness

London
University College London (UCL)
Engineering
Posted: 24 November
Offer description

Topic description

About the Project

Bacterial contamination and antimicrobial resistance (AMR) have progressively emerged as alarming public health concerns. For decades, these issues have been primarily addressed through the development and refinement of chemical therapeutics; however, such strategies, largely based on modifying existing compounds, are now approaching their limits in both effectiveness and safety. This PhD project aims to address this challenge through biomimetic engineering design, combining predictive in silico modelling with machine-learning techniques and microfluidic engineering to develop nature-inspired soft-nanorobots. Simultaneously, the research will initiate the development of a biomimicry-based framework with public health practitioners, community members and those with lived experience to promote a new understanding of biomimicry as a design principle to support engagement and implementation of the technology for future practice. Overall, these activities will contribute to advancing the design of technologies and frameworks that incorporate scientific, clinical, and community perspectives, fostering a more comprehensive understanding of illness and AMR.

This project combines machine-learning-augmented simulations and microfluidic engineering to explore the biomimetic design of antimicrobial nanotechnology. The engineering design will be supported with practice-based research to develop new ontological thinking and knowledge creation processes through integrating engineering and public health disciplines.

You will be hosted at UCL Arts & Sciences and collaborate with UCL Chemical Engineering and work closely with experts in in-silico engineering and applied machine-learning (Dr Francois Sicard), complex multiphase flows (Prof Panagiota Angeli), and pharmacy practice (Dr Ranjita Dhital).

The successful applicant should have or expect to achieve a Masters-level degree (1st or 2:1) in a relevant subject, e.g., Chemistry, Physics, Natural Sciences with an interest in interdisciplinary research in machine-learning-augmented computer simulations and experimental chemical engineering and are motivated by implementing sciences and practices related to public health impact of healthcare nanotechnologies.

Application open until 5th, January (13:00 UK time)

Studenship is expected to start on the 1st, October

Additional information about the project:

See the UCL EPSRC Landcape Award (UELA) website for details on how to apply with the Project ID - bd:

Funding Notes

This UCL EPSRC Landcape Award (UELA) Studentship is open to both Home and International fee status students, however EPSRC caps the number of International students and competition for this place will be particularly strong. The studentship is expected to start on 01-Oct- unless exceptional circumstances require an alternate start date. Exceptional circumstances include, but are not limited to, disability and caring responsibilities.

Starting date

-10-01

Funding category

Public funding alone (i.e. government, region, European, international organization research grant)

Funding further details

UCL EPSRC Landcape Award (UELA)

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Home > Jobs > Engineering jobs > Engineering jobs > Engineering jobs in London > Biomimetic Engineering Design of Biohybrid Soft Nanorobots to Combat Antimicrobial Resistance and Advance an Integrated Understanding of Illness

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