About the role
We are seeking an experienced Clinical Trials Operations Manager (Regulatory) to join the CTC Senior Management Group and provide strategic operational leadership across our regulatory-critical functions.
This is a senior, influential role with real autonomy. You will have oversight of:
1. Quality Assurance
2. Pharmacovigilance
3. Monitoring
4. Key elements of data management infrastructure
Working closely with the CTC Director, Clinical Leads and senior colleagues, you will shape how trials are set up, governed and delivered — ensuring compliance with GCP, MHRA and HRA requirements, while also improving efficiency, systems and timelines across a complex and varied portfolio.
You will:
5. Lead and develop Grade 7 and 8 operational specialists
6. Streamline and modernise SOPs, systems and infrastructure
7. Play a key role in MHRA inspection readiness
8. Act as a senior point of contact with regulators and partners
9. Represent the CTC at national and international forums
10. Contribute to centre-wide strategy and cross-CTU collaboration at UCL
This role is not about day-to-day trial delivery. It is about setting direction, solving complex problems, and enabling others to deliver safely, efficiently and at scale.
The post is funded for three years in the first instance, on a renewable Cancer Research UK programme grant.
Previous applicants need not apply.
About you
We’re looking for someone who already operates comfortably at senior CTU or sponsor level and wants to apply their expertise in a large, high-impact academic trials environment.
You will bring:
11. High-level knowledge of UK (and EU) clinical trials regulation, including pharmacovigilance
12. Strong understanding of QA, monitoring and clinical data management
13. Experience delivering IMP trials (licensed and unlicensed)
14. Confidence providing regulatory leadership and judgement, not just compliance
15. Proven line management and leadership experience
16. The ability to improve systems and infrastructure, not simply maintain them
17. A pragmatic, solutions-focused approach to complex operational challenges
You enjoy working independently, influencing senior stakeholders, and balancing regulatory rigour with real-world delivery in a collaborative, multidisciplinary setting.
What we offer
The opportunity to play a senior leadership role in one of the UK’s most respected cancer trials centres
Work that has direct, measurable impact on patient care and clinical practice
A supportive, expert and highly collaborative culture
Hybrid working with flexibility around start and finish times
(staff are expected to work on site around 60% FTE, typically 3 days per week for full-time roles)
Competitive Grade 9 salary (£68,–£76, per annum, including London Allowance)
Access to UCL’s extensive professional development, wellbeing and benefits package
UCL is consistently ranked among the world’s leading universities and is committed to inclusive, sustainable and flexible ways of working.