We are looking for a talented and motivated Research Associate to join the lab of Professor Jason Carroll, based in the internationally renowned Cancer Research UK Cambridge Institute https://www.cruk.cam.ac.uk/, located on the Cambridge Biomedical Campus.
Overview
The Carroll lab is focused on understanding mechanisms of transcription factor (TF) biology across cancer types. We take a genomic, proteomic and molecular approach to delineate mechanisms, with particular emphasis on defining mechanisms that contribute to tumorigenesis and drug resistance.
We are looking for a Research Associate to progress projects within the laboratory. Our lab is interested in exploring the role of TFs across cancer types using our tools, in conjunction with recent advances in various cancer systems. This will involve detailed pathway biology and focus on characterising chromatin complexes in cancer.
We are exploring saturation mutagenesis approaches for screening candidate TFs, to identify functional amino acid residues required for tumour growth and/or metastasis.
We are looking for someone willing to learn new molecular approaches. While we’re particularly keen to recruit someone with pancreatic or prostate cancer experience, we are open to all applicants from any cancer background.
Responsibilities
* Work independently and apply problem‑solving skills to troubleshoot challenging technical issues.
* Contribute to running various projects within the laboratory and present work regularly at lab meetings.
* Co‑write grant applications to support the specific research projects they are working on.
* Explore funding opportunities for future independent research.
Person Specification
Applicants should have, or will soon be awarded, a PhD in Biology or another relevant biological science discipline. Applicants should demonstrate strong molecular biology laboratory experience and biochemical expertise. Experience in cancer biology, particularly with pancreatic or prostate cancer, is an advantage. Experience working with in‑vivo mouse models (PDX, autochthonous models) and genomics would also be advantageous. Applicants should have excellent written and spoken English communication skills and demonstrate strong attention to detail.
Appointment at Research Associate level is dependent on holding a PhD. Those who have submitted but not yet received their PhD will initially be appointed as a Research Assistant (Grade 5, Point 38, £34,610) moving to Research Associate (Grade 7) upon confirmation of their PhD award. The funds for this post are available for 24 months in the first instance. Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) and a security check.
Reference: SW49430
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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