Job description
Site Name: UK London New Oxford Street
Posted Date: Apr 16 2026
Position Summary
Responsible to lead medical and scientific staff within the SERM (Safety Evaluation & Risk Management) group and defining and driving the strategy and vision of clinical safety and pharmacovigilance activities in alignment with Global Safety business strategies.
Responsibilities
* Lead and line manage the SERM group (10 team members) responsible for marketed HIV assets with ongoing clinical development from first-time-in-human studies through to regulatory submission; include resource and team management, coaching, influencing others, collaborative working, decision making, change management, partnership, and relations management.
* Implement policy, processes and support the implementation of operational and strategic plans.
* Ensure scientifically sound review and interpretation of data and management of safety issues and escalates safety issues identified through the safety review process to senior management and safety governance as appropriate; make recommendations for further characterization, management, and communication of safety risks.
* Focus on efficiency and effectiveness to meet the needs of patients and HCPs; support the pharmacovigilance and benefit-risk management of the assigned portfolio of GSK global assets to ensure patient safety globally.
* Expert in clinical safety and pharmacovigilance activities; demonstrate sound judgement and decision making in safety evidence generation, benefit-risk assessment, causality assessment, evaluation of safety signals, and proactive risk management, including management of labelling changes, physician and patient education and monitoring of safety issues in real world.
* Coach and mentor SERM colleagues in scientific/medical aspects of signal evaluation methodology and risk management and preparation of regulatory safety reports and other documents.
* Demonstrate track record of quality decision making and creative problem resolution in critical situations, based on assessment of all relevant supporting and conflicting information and understanding of the wider context.
* Provide excellent medical/scientific judgement, strong analytical skills, proactive approach in drug safety and high sense of urgency.
* Champion/sponsor safety governance by developing safety strategy and execution for products in clinical development and post-marketing settings; anticipate, detect and address product safety issues and ensure risk-reduction strategies are implemented appropriately.
* Lead cross-GSK activities such as safety advisory panels; interface with and assume ad hoc membership of a Senior Governance Committee.
* Engage and contribute to the broader GSK and pharmacovigilance environment outside GSK with confidence, impact, integrity and professionalism.
* Demonstrate ability to affect department or product strategies with global considerations; build strong collaborative relationships; lead a team in a matrix setting; demonstrate resilience and adaptability; oversee SERM contribution to due diligence activities.
* Excellent communication (verbal, written) and influencing skills internally and externally; influence others external to GSK to meet organisational objectives; recognised as an authority with expert knowledge of relevant pharmacovigilance regulations and methodologies.
Qualifications
* Medical degree for Senior Medical Director or Health Sciences/Health Care Professional degree (BSc, MS, PhD, RN/BSN/MSN, NP, RPh/B Pharm/Pharm D) for Senior Scientific Director.
* Completion of formal postgraduate clinical training, clinical residency or specialty training for Senior Medical Director.
* Comprehensive experience in the pharmaceutical or biotech industry working in pharmacovigilance or drug safety.
* Significant pharmacovigilance experience relating to safety evaluation and risk management, encompassing both clinical development and post-marketing activities.
* Knowledge/experience of international pharmacovigilance requirements (ICH, GVP modules, CIOMS initiatives) and drug development and approval processes.
* Experience working in large matrix organizations.
* Prior experience in the HIV therapy area is desirable but not essential.
Working pattern and location
This role is based in the United Kingdom and is hybrid, combining office presence with remote work to support collaboration and flexibility.
Benefits & Impact
You will have direct impact on patient safety and on the scientific approach we take to benefit-risk decisions. You will grow your leadership skills and expand your influence across scientific, regulatory and clinical stakeholders.
Equal Opportunity Employer Statement
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
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