Join our high-performing Oligonucleotide Production team in Southampton—a vibrant coastal city offering the perfect balance of professional opportunity and quality of life, with excellent transport links.
We are seeking a Senior Scientist with deep expertise in downstream processing modalities including oligonucleotides/Peptides to lead analytical strategy and contribute to the development and production of high-quality modified Oligonucleotides
Key responsibilities
* Lead and oversee downstream workflows, supporting purification, analysis and characterisation of oligonucleotides including HPLC, SDS-PAGE, TFF and UPPL-MS
* Stay abreast of emerging technologies and methodologies in nucleic acid chemistry
* Drive method development and troubleshooting with purification techniques
* Ensure rigorous documentation
* Collaborate cross functionally across the organisation
* Coach and mentor junior team members
Skills and Experience
* PhD in Chemistry and/or related discipline
* Proven hands-on experience working with oligonucleotides/peptides is highly desirable within Academia or Industry (Small molecule experience will also be considered)
* Experience of UF/DF and TFF is highly desirable
* Strong background in purification and downstream processing techniques - HPLC, UPLC-MS, SDS-PAGE
* Experience working in ISO/GMP regulated environments is highly desirable
* Self-starter with the ability to lead projects which require troubleshooting and problem solving
* Detail orientated, strong communicator who can work under pressure in a fast-changing environment
What we can offer you:
* 25 days annual leave plus 8 paid bank holidays
* Contributory pension scheme (6% employer contribution)
* Flexible working hours
* Life Assurance (x4 salary)
* Long service awards
* Reward and recognition scheme
* Employer Assistance Programme with 24/7 remote GP service
* Annual flu jabs
* Cycle to work scheme
* Corporate discount on gym membership
* Savings and discounts
* Reimbursement of professional membership fees
* Referral incentives
* Social events
* Volunteering days
Biotage is a global supplier and solutions partner to a wide range of customers within drug discovery and development and analytical testing. With strong expertise in separation and purification technologies, and a focus on leveraging intelligent workflow solutions, we aim to efficiently support the advancement and protection of human health. Learn more