Overview
The CRUK Cambridge Institute (CI), a department of the University of Cambridge, is one of Europe\'s top cancer research institutes. We are situated on the Addenbrooke\'s Biomedical Campus and are part of both the University of Cambridge School of Clinical Medicine, and the CRUK Cambridge Centre. The Institute is home to 18 research groups which cover a spectrum of research from basic experimental and computational cancer biology through translational cancer research to clinical application. The Institute\'s scientific Core Facilities work in partnership with the Institute\'s Research Groups and are a repository for deep technological expertise and knowledge, playing a fundamental role at the heart of the Institute\'s research community.
The Cambridge Institute Genomics Core (CIGC) provides Next-Generation Sequencing (NGS) services for CRUK CI as well as the wider University and collaborative laboratories across The Cambridge Biomedical Campus. The CIGC supports translational research by providing variety of bulk DNA/RNA library preps (from multiple suppliers), sequencing service (MiSeq, NextSeq2000, NovaSeqX Plus, ONT PromethION24) and single cell library prep service including but not limited to 10X workflows. We support cell isolation (CellenOne) for downstream single cell genomics applications and currently are expanding spatial single cell platforms offering 10X Visium SD, 10X Visium HD and 10X Xenium.
Responsibilities
* Assist in the provision of bulk DNA/RNA library preparation and sequencing operations.
* Carry out single-cell library preparation and spatial services support.
* RNA/DNA sample quality control, bulk DNA/RNA library preparation using standard kits from different suppliers.
* Single-cell sample receipt and processing, LIMS curation, and sequencing on Illumina and ONT platforms.
* Data analysis of quality and interaction with users of the services.
* Involvement in pilot experiments, testing and implementing new technologies including novel library preparation for bulk DNA/RNA and single cells and spatial platforms, for poor and good quality materials.
* Work under own initiative for most daily duties and troubleshoot issues; collaborate with technical support teams and escalate to a senior member as needed.
Qualifications
* Degree in biological or biotechnological sciences.
* Experience with a diversity of molecular biology techniques including PCR/qPCR, DNA/RNA/single cell library preparation, NGS short and long read sequencing.
* Excellent communicator and team player; ability to bring a positive impact to the Core.
Additional information
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Fixed term: The funds for this post are available for 1 year in the first instance.
This post may require some out of hours working and travel to national seminars/meetings.
Interviews are expected to be held on the 18th and 19th November.
If you have any queries regarding the application process, please contact: mailbox-hr@cruk.cam.ac.uk.
Please quote reference SW47642 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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