We are seeking
an experienced and enthusiastic individual for the role of research technician specialising in next generation sequencing and imaging. Your work will help to accelerate translation of genetic findings to treat four key musculoskeletal diseases: osteoarthritis, carpal tunnel syndrome, frozen shoulder, and Dupuytren disease. In this role you will be responsible for the development and implementation of standardized protocols for patient blood and tissue sample processing for nucleic acid extraction or imaging. You will be liaising with teams across the Functional Genomics setting to ensure adequate samples are available for sequencing as well as teaching experimental techniques to new laboratory members and providing supervision of new lab members within the laboratory. You will be responsible for managing DNA and RNA extraction from human blood and tissue samples prior to genotyping, methylation and transcriptome analysis. About You You will hold a BSc or MSc in biological science or equivalent experience together with previous laboratory experience of methods including nucleic acid extraction from tissues and immunohistochemistry as well as of next generation sequencing library preparation. You will have the ability to work co-operatively as part of a team, as well as independently while taking personal responsibility for assigned tasks. You will demonstrate basic computing skills, including use of Microsoft Word and Excel together with the ability to learn and develop new techniques, and to troubleshoot them. You will be able to clearly demonstrate the ability to keep extensive and detailed records that comply with necessary legislation (e.g. the human tissue act). Experience in training individuals in laboratory techniques as well as experience of basic analysis of sequencing or spatial mapping data are desirable. Application Process