Overview
The Quality function promotes quality and compliance through the product life-cycle within the wider manufacturing and production operations at GSK Barnard Castle Manufacturing Site. The Quality function at GSK plays a critical role in ensuring our products meet the highest standards of safety, efficacy, and compliance. As part of this team you will uphold our commitment to delivering high-quality medicines and vaccines, and healthcare products to patients and consumers around the world.
Job Purpose
Reporting into the site’s Quality Director, The Quality Technical and Validation Senior Manager provides oversight and expertise to support the validation of new products, equipment, cleaning processes, computerised systems and facility projects across the Barnard Castle site. This role is responsible for ensuring compliance with regulatory standards, driving process simplification, and fostering collaboration with on-site and off-site teams to deliver high-quality outcomes.
Direct Reports – The role manages approximately 13 direct reports.
Key Responsibilities (include)
* Responsible for Operational Quality oversight and deployment of GSK’s quality strategy within site Engineering, Manufacturing Science and Technology (MSAT) and Logistics in line with GSK’s internal policies and procedures as well as all regulations and laws.
* Drive the site’s validation strategy across key areas including process validation, cleaning validation, equipment qualification and facility validation, aligning with regulatory expectations and GSK’s standards.
* Provide validation expertise for New Product Introductions (NPI) for seamless integration from development through to commercialization, and post-approval lifecycle changes.
* People management, succession planning and team development to ensure retention. Train, coach and motivate the management team and employees towards Continuous Improvement, GMP, and provide active development for direct reports and key talents within the Quality Technical and Validation team.
* Serve as site validation authority for regulatory submissions, preparing and approving validation protocols and reports to ensure compliance and readiness for regulatory submissions. Manage interface with regulatory authorities (e.g., MHRA, FDA) by providing expertise on validation and quality activities (ensure positive outcomes during inspections and audits).
* Work cross-functionally with above-site teams, as well as with Manufacturing, Engineering, Quality, and R&D, to align validation and quality activities with broader business objectives and to achieve seamless project delivery.
* Develop and implement strategies to simplify validation and quality processes, driving efficiency, continuous improvement, and "Right First Time" execution.
* Establish and maintain robust validation frameworks, standards, and procedures to ensure consistent execution of activities across site functions (adhering to GSK Quality and EHS requirements).
* Build and strengthen partnerships across GSK’s network (including R&D, Primary Supply Sites, Product Quality Centres of Excellence, and external suppliers) to drive alignment, knowledge-sharing, and best practices for validation and quality activities.
About You
As this role is multi-faceted and includes liaising with a wide variety of on-site production and operations teams, you will be a self-motivated person who has strong experience of working in validation within a complex highly-regulated manufacturing site. People management skills / experience are also required to deliver in this role. You will be resilient and calm under pressure, with strong people skills and a proven ability to influence people to achieve objectives and drive performance. You will have a strong continuous improvement mindset. Effective written and verbal communication and excellent interpersonal skills, as well as the ability to organise and prioritise workload are considered essential skills.
About Barnard Castle
GSK Barnard Castle is a key secondary manufacturing site. We have invested heavily in industry 4.0 state of the art bespoke equipment to support sustained new product introductions and volume increases. As a key supplier of some of GSK’s blockbuster products the site contributes revenues of ~$2Bn annually.
Closing Date
CLOSING DATE for applications: Wednesday 5th of November 2025.
Basic Qualifications
* Degree in relevant Scientific, Technical or Engineering discipline (or equivalent experience, ideally gained working in a Pharmaceutical Manufacturing Facility or similar highly-regulated industry).
* Relevant validation knowledge/experience.
* Management experience.
* Knowledge of current Good Manufacturing Practice (cGMP) requirements.
* Knowledge and application of Quality Management Systems (QMS).
* Knowledge of internal and external audit processes (eg; inspection readiness).
Benefits
GSK offers a range of benefits to its employees, which include, but are not limited to:
* Competitive base Salary
* Annual bonus based on company performance
* Opportunities to partake in on the job training courses
* Opportunities to attend and partake in industry conferences
* Opportunities for support for professional development and chartership
* Access to healthcare and wellbeing programmes
* Employee recognition programmes
If you would like to learn more about our company wide benefits and life at GSK we would suggest looking at our webpage Life at GSK | GSK.
Why GSK? Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.
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