We are currently looking for a Technologist to join our clients Cell Expression Systems R&D team in Cambridge, to contribute to the execution of analytical activities for multiple projects.
Core responsibilities include:
* Assist with sample analysis to generate data for decision making across multiple projects with other senior analytical scientists
* Perform sample purification, product quantification and product quality analysis including but not limited to PrA HPLC, SEC, CE-SDS and icIEF
* Solution preparations – including analytical buffers, media and feed where required
* Monthly mycoplasma testing
* General lab housekeeping e.g. stock checks, instrument calibrations when required
* Work closely with multiple R&D teams to deliver solutions or improvements in recombinant protein manufacturing
* Maintain accurate and timely records to appropriate quality standards
* Actively keep aware of relevant academic literature
* Contribute ideas and opinions to aid the development of new methods and/or technologies
* 85% lab-based role using experience and knowledge
Key requirements:
* Previous practical experience in an analytical laboratory with a focus on protein characterisation, with aseptic practical experience
* Knowledge and practical expertise in chromatography and electrophoresis techniques (e.g. ProA HPLC, SEC, CE-SDS) in the field of protein characterization
* Knowledge of affinity purification techniques
* A good general background in established analytical methods in the industry, including the strengths and weaknesses of various approaches
* Previous practical experience in an analytical laboratory with a focus on protein characterisation
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