About Level Zero
Level Zero is pioneering next-generation biosensor technology for precise, real-time monitoring of critical endocrine biomarkers. Recognised as one of the top 20 startups across all categories worldwide at TechCrunch Disrupt 2024—and backed by top-tier organisations like SOSV and Entrepreneur First—we're pushing the boundaries of biochemistry and nanotechnology to revolutionize personalised health.
Founded by two seasoned engineers, we bring extensive experience in R&D, technical innovation, and commercial strategy to transform the way people monitor their health. Our mission is bold: to revolutionise health management by delivering clinical-grade data directly to individuals, wherever they are.
We're seeking driven innovators to join us in pushing the boundaries of biosensing and health tech, making personalised health monitoring a reality for everyone. To achieve this ambitious vision, we're assembling the best team in the world—dedicated to turning cutting-edge science into life-changing, real-world solutions.
About The Role
We are excited to welcome an Immunoassays Development Scientist to join our team. The ideal candidate will have expertise in developing immunoassays for the detection of small molecules using antibodies or aptamers. Experience in the optimization of assays to improve biosensor performance metrics (sensitivity, specificity, limit of detection, etc.), is essential. A background in aptamer based bioassays is highly desirable.
This is a full-time, in-person role primarily based in London.
Some examples of what you might do:
* Design and optimize aptamer or antibody based immunoassays (e.g. with colorimetric or fluorometric detection, plate reader based, LFA based, etc.) targeting diverse analytes in different biological matrices
* Evaluate and improve the performance of immunoassays (focusing on sensitivity, specificity, LOD, etc.)
* Characterize and screen binding performance of aptamers and antibodies to a variety of small molecule targets in different biological matrices
* Work closely with the broader Biosensing team to design and develop complex bioanalytical assays utilising a diverse array of detection methodologies (e.g. colorimetric, fluorometric, electrochemical, etc.)
* Work closely with the LFA team to develop immunoassays into later flow assays
* Collaborate with cross-functional teams to integrate immunoassays into biosensor devices or delivery platforms
* Analyse and report experimental data clearly, maintaining thorough technical documentation
What You Bring
* A Ph.D. in Biochemistry, Molecular Biology, Immunology, or a related field. Postdoctoral or industrial experience is a plus.
The ideal candidate will possess expertise in the following areas:
* Strong expertise in the design, development and optimization of immunoassays (e.g. ELISA, immunoflorescence, etc.).
* Experience in the conjugation of biomolecules to solid supports.
* Experience in the functionalization of biomolecules like antibodies and aptamers.
* Experience in using and interpreting biophysical and biochemical characterization techniques (e.g. gel electrophoresis, UV-Vis spectroscopy, SPR, BLI, ITC, flow cytometry etc.)
* Ability to design experiments, interpret data, and solve problems independently in a fast-paced environment.
* Excellent communication skills and ability to work collaboratively in multidisciplinary teams.
Nice to have:
* Experience in the development of aptamer based immunoassays.
* Experience in the development of immunoassay having small molecules as targets
* Experience working with hydrophobic molecules.
* Experience in assay validation, verification and transfer to manufacturing
* Knowledge of high-throughput sensing platforms and assay development.
Who You Are
* We value culture as much as we value technical expertise, creating an environment that's equal parts collaboration, curiosity, and fun
We're a fast-paced, mission-driven young team on a quest to make a lasting impact, fueled by uncompromising integrity, unwavering support for one another, and the thrill of exploring uncharted territories. Our passion for excellence drives everything we do, and we welcome individuals who share our commitment to shaping the future.
If our vision excites you, here are the qualities we look for:
* You live and breathe integrity, tackling challenges with honesty and transparency
* You're a self-starter who loves diving into the unknown, collaborating on complex problems, and taking full ownership of results
* You excel at open, clear communication and see every piece of feedback as a springboard for growth—especially in a science and data-focused environment
* You're motivated by creating real impact, particularly when it comes to advancing human health
* You strike a balance between independence and collaboration, knowing when to seek support or invite others to join in
* You're confident in defending your ideas, while also valuing respectful, constructive debate as a path to better solutions
* You thrive in the dynamic atmosphere of a startup, constantly evolving your skill set and fearlessly applying what you learn
What We Offer
* A full-time role with a competitive salary and equity options, reflecting our value in your expertise and potential
* An environment where you'll collaborate directly with the founding team at a leading biosensor startup, gaining access to industry experts and thought leaders
* The chance to grow with us, including ample opportunities for leadership, career advancement, and exploration
* Travel to New York and other potential sites for R&D purposes
* The excitement of working on cutting-edge technology, shaping strategic decisions, and driving innovation at an early-stage venture alongside a superstar team
Be Part of Our Journey
If you're ready to be at the forefront of biosensing innovation and thrive in fast-paced, learning-rich environments, we'd love to hear from you.
If your skills and experience do not align perfectly with this role, yet you believe you have something unique to offer, we're keen to listen. Reach out to us with a short statement on how you can contribute and let's discuss where you might fit into our team.