At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
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Position Summary
Key Responsibilities
In this role, you will:
1. Apply expertise in human genetics, statistical genetics, genetic epidemiology, or a related discipline to support the development of new medicines.
2. Contribute to the ongoing development and iteration of scaled and automated genetic assessment tools to support the advancing science of drug target identification and validation.
3. Develop and/or critically evaluate new methods to derive and apply genetic insights to support the development of therapeutic target hypotheses.
4. Perform and apply at-scale and bespoke computational and statistical analyses (e.g., GWAS, WGS, Mendelian Randomization, rare variant association testing, and variant to gene mapping) and implement new analytical methods to infer molecular mechanisms to elucidate and interrogate therapeutic hypotheses
5. Evaluate genetic and causal biology evidence to support therapeutic target hypotheses and provide clear and concise communication of results and interpretation to peers and leaders.
6. Collaborate effectively in multi-disciplinary teams (internal and external) to answer complex scientific questions.
7. Identify and implement creative solutions to address challenging scientific questions.
Why You?
Basic Qualifications
8. Ph.D in human genetics, statistical genetics, genetic epidemiology, or related disciplines with strong computational and quantitative focus.
9. Experience in development, critical evaluation and application of analyses methods to answer complex scientific questions
10. Experience in performing analyses and the interpretation of findings of large-scale population based genetic studies (e.g., GWAS and WES/WGS approaches, MR and variant to gene mapping)
11. Experience evaluating and integrating genetic and genomic data to evaluate strength of causal genetic evidence (e.g., QTL mapping & integration, causal inference, pathway enrichment)
12. Proficient in programming/scripting in R or Python and working within cloud-based computing platforms (e.g., AWS and/or Google Cloud)
13. Experience in working with genetics databases and resources including key biobanks and disease-specific consortia data sources
Preferred Qualifications
14. Experience working in multi-disciplinary teams to answer scientific questions and influence scientific plans/project decisions.
15. Excellent communication skills to effectively convey complex scientific concepts to peers and leaders
16. Proactive and innovative mindset with the ability to identify and implement creative solutions and demonstrated strong problem-solving skills
17. Ability to work flexibly and adapt to changing priorities and timelines.
18. Passion for advancing the science of drug target identification and validation.
19. Experience in software development, both independently and as part of a team, developing well-documented solutions that other scientists can use, understand and debug. Strong understanding and experience with implementation of FAIR data principles.
Work model
#GSK-LI
• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $121,275 to $202,125. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.
Please visit to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.
People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.