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Postdoctoral fellow, human genetics, inflammation & immunology

Cambridge
Pfizer, S.A. de C.V
Posted: 15 September
Offer description

Overview

United States - Massachusetts - Cambridge

We’re in relentless pursuit of breakthroughs that change patients’ lives. Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world. Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.

Pfizer’s purpose is to deliver breakthroughs that transform patients' lives. The Research and Development organization strives to convert advanced science and cutting-edge technologies into impactful therapies. As a postdoctoral fellow you will apply innovative computational techniques to discover new disease mechanisms, which will expedite the delivery of top-tier medicines to patients globally.


What You Will Achieve

The systems immunology group in Pfizer’s Inflammation and Immunology research unit seeks an exceptional postdoctoral fellow with expertise in human genetics and computational biology to discover causal molecular and environmental risk factors for immune-mediated diseases. This project—which will involve collaboration with a vibrant community of human geneticists, immunologists, and computational biologists—will advance our understanding of the diverse, complex mechanisms underlying immune-mediated diseases.


How You Will Achieve It

* Contribute intellectually to the design and interpretation of a rigorous human genetics-led study of determinants of immune-mediated diseases
* Perform intricate analyses of individual-level genetic, molecular, demographic, and clinical data to discover novel risk factors for immune-mediated diseases
* Determine the causality of such risk factors using methods in human genetics
* Characterize genetic correlations between diverse immune-mediated diseases
* Explore and validate results across population-scale biobank datasets
* Interpret the immunological mechanisms and significance of all novel associations
* Publish in a high-impact journal


Must Have

* PhD in human/statistical genetics or related field
* Willingness to make a minimum 2-year commitment
* No more than 2 years of post-degree experience
* Successful record of scientific publications with at least one first-author manuscript published or submitted for publication in a peer-reviewed journal
* Familiarity with common methods for analysis/associations with individual-level genetic data, and post-GWAS analyses (S-LDSC, MR, etc)
* Experienced with common statistical methods/tests; strong coding experience
* Willingness to learn about immune-mediated diseases
* Ability to devise innovative bespoke analyses and work independently
* Excellent written and verbal communication skills, including communication with non-scientists, and high attention to detail


Nice to Have

* Experience working with biobank datasets
* Experience with basic and/or translational immunology
* Experience with analysis of single cell RNA/CITE-sequencing data


Additional Information

Location: On premise, hybrid. Relocation support available. Last day to apply September 25th, 2025.


Salary & Benefits

The annual base salary for this position ranges from $62,700.00 to $104,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs including a 401(k) plan with Pfizer Matching Contributions, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits (medical, prescription drug, dental and vision).

Relocation assistance may be available based on business needs and/or eligibility. Benefits details vary by location.


EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable laws governing nondiscrimination and work authorization. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Accessibility: Pfizer is committed to accessibility. If you need assistance accessing our website or completing the application process, please email disabilityrecruitment@pfizer.com for accommodations.

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