Overview
We are seeking a bright and enthusiastic research assistant to join the Spatial Profiling and Annotation Centre of Excellence (SPACE) at the CRUK Cambridge Institute, University of Cambridge. The role involves developing and performing assays in histology and spatial “omics” (with a focus on spatial transcriptomics and multi-omics) on tumour clinical samples and tumour models, and contributing to the development of new technologies and models in this field.
About SPACE
The SPACE centre of excellence is a multidisciplinary group focused on improving spatial molecular profiling technologies (spatial proteomics, transcriptomics, genomics) and applying them to cancer biology and beyond, through large collaborations within and outside of Cambridge. It includes spatial omics technologies, a world-class data processing centre, and dedicated staff including biologists, technologists and bioinformaticians. Projects include developing predictors for triple‑negative breast cancer therapy response, studying ovarian cancer tumour heterogeneity and metastatic dissemination, and investigating glioma grade transitions.
The Hannon group
The Hannon group is renowned for its contributions to RNA biology and cancer research, developing innovative tools for cutting-edge questions. The group has established a robust pipeline for 3D spatial characterization of tumours and tissues, with spatially and temporally resolved single-cell transcriptomics and proteomics.
Responsibilities
* Receive samples and design/perform experiments in alignment with SPACE projects.
* Accurately report results and maintain high quality and reproducibility in all experimental work.
* Collaborate closely with SPACE team members and collaborating laboratories; contribute to project goals and timelines.
* Potentially become embedded in a particular SPACE project and may pursue relevant study opportunities (e.g., MSc or PhD) at the University of Cambridge if offered.
Qualifications and experience
* Excellent laboratory skills in molecular biology, histology or cell biology.
* Desirable: background in genomics and cancer research.
* Experience with in situ technologies (e.g., single molecule FISH, in-situ transcriptomics, multiplexed IHC) or similar is encouraged.
* Experience with tissue culture, RNA extraction and purification, histology, microscopy or bioinformatic analysis is beneficial but not strictly required.
* Strong initiative, independent thinking, and good communication/organizational skills; ability to work both independently and in a team.
* A BSc or MSc in biology, biochemistry, natural sciences or a related field, plus practical research experience.
Employment details
Fixed-term: The funds for this post are available for 12 months in the first instance.
Other information
As a member of the Hannon laboratory, you will have the opportunity to contribute ideas to ongoing research activities. We are committed to an inclusive and supportive working environment that fosters scientific excellence.
Application process
To apply, click the "Apply" button below to register an account with our recruitment system (if you have not already) and apply online.
For queries regarding the application process, please contact: mailbox-hr@cruk.cam.ac.uk.
Please quote reference SW46994 on your application and in any correspondence about this vacancy.
Equal opportunity and eligibility
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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