Biostatistician in Statistical Methodology – Associate Director
Location: Cambridge
Salary: Competitive
At AstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We continuously forge partnerships to pursue world‑class medicines. Our Oncology Biometrics department is an integral part of the Oncology R&D organisation.
We drive excellent design in order to generate the appropriate data needed for quality decision making. The goal of Oncology Biometrics is to deliver value to the pipeline by excellence in delivery, improved decision making and engaging and shaping the external environment whilst accessing and implementing innovative solutions.
Responsibilities
Joining a team of statistical methodology experts, you will provide key input as you work to find solutions to problems at critical stages in the drug development cycle. This involves producing pragmatic solutions within tight time scales, contributing to or leading capability build in innovative methodological approaches in oncology R&D, providing expert consultancy on key issues for fellow statisticians and medical scientists, and participating in strategic activities such as capability build projects. You will also develop and implement new methodology, interact with external scientists and regulators through publications, presentations and cross‑industry collaborations, and proactively identify new areas where Statistical Innovation can add value.
Qualifications
* MS or PhD in Statistics or related discipline, plus several years of independent academic research and/or clinical drug development experience.
* Documented ability to deliver innovative statistical solutions in drug development and evaluation, study design, data analysis and interpretation.
* Familiarity with oncology‑related biomarkers (e.g., ctDNA), translational research methodologies, and regulatory requirements for biomarker evaluation.
* Track record of research and methodological development in statistics.
* Desire to apply scientific competence on practical problems for the benefit of patients.
Desirable
* Knowledge of Bayesian methods and applications and statistical methods related to biomarkers.
* Research experience in the development of statistical methodology related to design of late‑phase clinical trials.
* High level of competence in global and cross‑skilled collaborative working.
* Strong knowledge of programming in R and/or SAS.
* Broad awareness of statistical issues against the evolving scientific and regulatory landscape.
Equal Employment Opportunity Statement
Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
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