A Wellcome-funded postdoctoral position is available in the Straube lab to investigate how molecular motors dynein and KIF1C organise microtubule arrays and transport intracellular cargoes. The postholder will generate knock-in cell lines in iPSCs, differentiate into neurons and other suitable lineages and use live cell imaging and quantitative image analysis to understand microtubule organisation, motor protein conformation and motility. Further, recombinant protein complexes will be prepared and electroporated into cells. The post holder will become a member of the Centre for Mechanochemical Cell Biology and Warwick Medical School benefitting from an outstanding scientific environment and access to state-of-the-art research facilities.
Informal enquiries including a CV and motivation statement should be sent to a.straube@warwick.ac.uk.
The posts are funded by a Wellcome Investigator Award to investigate how cargo transporters organise the tracks along which they transport cargoes. You will be part of an international, well-resourced team of researchers with access to state-of-the-art equipment (including access to a range of light microscopy systems including spinning disk confocal, TIRF, lattice light sheet and optical tweezers) and a vibrant scientific community with excellent internal and external seminar programmes.