Job Description
We have an exciting opportunity for a Metabolomics Bioinformatician to help drive the invention of safe and sustainable active ingredients in Product Safety by contributing to the cutting-edge research and development within our dynamic and highly talented team. Key responsibilities will include:
* Performing metabolomics data processing, analysis and interpretation with a primary focus on toxicology.
* Seeking out the latest developments in data analysis, in consultation with senior technical experts, assessing their potential use to support projects.
* Developing and maintaining data handling and data retrieval solutions, while representing metabolomics in digital infrastructure projects.
* Contributing to the development of multi-omics integration solutions in multi-disciplinary project teams.
* Communicating the output of metabolomics datasets to a wide and varied community of end users.
* Working with contract organisations and/or academic collaborators to define and develop solutions/tools/workflows to support Syngenta scientists.
* Supporting data generation when required.
* Networking within Syngenta and the external bioinformatics community to ensure best use of resources and opportunities.
Qualifications
What we are looking for?
* Educated to degree level or higher (MSc or PhD) and preferably with post-graduate experience in metabolomics, biochemistry, toxicology or similar.
* In-depth metabolomics experience, including
o sample preparation, quality control procedures and analytical chemistry on data processing requirements.
o processing of metabolomics data using specialist software (vendor or open source).
o bioinformatics and pipeline development skills in e.g. KNIME, R and Python.
o peak picking, peak annotation, data normalisation and filtering techniques.
o experienced in multivariate statistics, differentially abundant metabolite selection and pathway analysis.
* Good level of biochemistry knowledge.
* High level of attention to detail and compliance.
* Ability to present complex results to non-specialists in a clear and concise manner.
* Self-motivated learner adept at building relationships.
Desirable skills and experience
* Experience with Thermo Orbitrap MS and software: Xcalibur, Freestyle, Tracefinder, Compound Discoverer, LipidSearch.
* Experience with multiple application areas of metabolomics (in vitro, plant, environmental, mammalian, human etc).
* Biologically contextualising metabolomics results.
* Familiarity with multi-omics data integration.
* Ability to deliver technical leadership in defined areas.
Additional Information
Our site
Jealott's Hill International Research Centre UK is situated in pleasant semi-rural surroundings between Bracknell and Maidenhead and is the place of work for approximately 800 Syngenta scientists and support staff. Jealott’s Hill is one of the main global research and development sites and key activities include research into discovery of new active ingredients, new formulation technologies, product safety and technical support of our product range.
What we offer
* Extensive benefits package including a generous pension scheme, bonus scheme, private medical & life insurance.
* Up to 31.5 days annual holiday.
* Campus environment.
* A position which contributes to valuable and impactful work in a stimulating and international environment.
* The chance to work with and learn from highly qualified and experienced employees.
* Learning culture and wide range of training options.
Syngenta has been ranked as a top 5 employer and number 1 in agriculture by Science Journal.
Syngenta is an Equal Opportunity Employer and does not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Learn more about our D&I initiatives here:
Jealott’s Hill has Disability Confident certification.
We are committed to making all stages of our recruitment process accessible to all candidates and our Jealott’s Hill site are a Disability Confident Level 2 Employer. Please let us know if you need any assistance or reasonable adjustments throughout your application and we will do everything we can to support you.