Skin Bioassay Senior Scientist
Nottingham | On-site
We are seeking a Skin Bioassay Senior Scientist to join a growing CRO environment developing advanced in vitro skin models and bioassays for both pharmaceutical and cosmetic applications.
This role is part of a strategic expansion of in-house skin capabilities, supporting both ongoing projects and the development of new model systems. You will play a key role in generating high-quality datasets, developing human-relevant skin models, and delivering impactful assay results for clients.
Working within a collaborative, fast-paced laboratory environment, you will contribute to the development of next-generation skin models, including reconstructed and full-thickness systems, while supporting a broad range of client-driven and internal projects.
Responsibilities:
Skin Model Development
Develop and optimise in vitro skin models, including:
Reconstructed Human Epidermis (RHE) models
Full-thickness or full-skin equivalent systems
Contribute to the evolution of increasingly complex, physiologically relevant modelsAssay Development & Delivery
Design and execute cosmetic and skin-related bioassays, including:
Cell proliferation and viability assays
Cytokine release and inflammatory markers
Barrier function and sensitivity assessments
Analyse and interpret experimental data, ensuring generation of robust, client-ready datasetsMolecular & Analytical Techniques
Apply a range of techniques including:
ELISA and immunoassays
qPCR and molecular biology workflows
Plate-based assay readouts
Use imaging and histology-based approaches to assess skin structure and functionApplied Skin Science & Testing
Evaluate cosmetic formulations and active compounds
Investigate:
Ageing processes and protective effects
UV response (using in-house UV systems)
Key skin proteins such as keratin and structural markersProject Delivery & Lab Operations
Deliver experimental work in line with project timelines and client expectations
Prepare SOPs, reports, and technical documentation
Troubleshoot experiments and contribute to continuous improvement initiatives
Support a collaborative CRO environment including potential client interaction
About You
You are a hands-on scientist with experience in skin biology and in vitro model systems, comfortable working in a fast-paced, applied research or CRO environment.
You'll bring:
Experience working with in vitro skin models (essential)
Experience developing RHE (Reconstructed Human Epidermis) models
Strong laboratory experience across cell-based assays and bioassays
Knowledge of ELISA, immunoassays, qPCR, and cell culture techniques
A practical, delivery-focused mindset with strong attention to detailHighly desirable:
Exposure to full-skin equivalent or 3D skin models
Experience in cosmetic testing, skin ageing, or UV response studies
Background in CROs or applied commercial researchPhD candidates or those with 2-3 years of relevant industry experience are both encouraged to apply.
This is a great opportunity to join a growing organisation at a key stage, where you will not only deliver projects but also help shape the future direction of skin model development within the business.
Apply now by attaching your CV in Word, or contact Paige Keenan for further information about this new role:
Guidant, Carbon60, Lorien & SRG - The Impellam Group Portfolio are acting as an Employment Business in relation to this vacancy