Postdoctoral Scientist
Starting Salary: £41,344
Fixed term: 3 years
MRC Laboratory of Molecular Biology, Cambridge, UK
We are looking for a postdoctoral scientist to join the group of Sjors Scheres to work on cryo-EM structure determination of amyloid filaments. Depending on the background of the candidate, the project would explore either laboratory-based model systems (with purified recombinant proteins or cells) for the formation of amyloid filaments with the same structures as those observed in human brain; or the ultra-structural organisation of amyloid filaments in brain tissue using correlative light and electron microscopy and cryo-electron tomography.
You will be part of our bubbly, multi-disciplinary team that operates in close collaboration with the group of Michel Goedert, you will become an expert in experimental cryo-EM structure determination, and you will benefit from further interactions with the wider scientific community at the MRC-LMB. You are highly motivated to work on amyloids and have a PhD in a relevant subject. A strong background in protein biochemistry/biophysics, previous experience with amyloids, or expertise in cryo-EM/ET will be an advantage.
Group web site: www2.mrc-lmb.cam.ac.uk/groups/scheres
This is a three-year training and development position suitable for you if you have recently completed your doctoral studies, or you are looking to move into a new research discipline and/or need to further develop your research skills. Working with our world class scientists you will be working in an Institute renowned for its excellent scientific facilities and high-quality research.
The LMB has a collaborative working culture and state-of-the-art building based on the Cambridge Biomedical Campus. We have on-site parking, cycle enclosures and excellent public transport links to the site. We have a staff restaurant with roof terrace and access to a Campus nursery and sports and social facilities. You will be eligible to join our defined benefit pension scheme, a holiday entitlement of 40.5 days (including bank holidays and privilege days) and a generous employee discount scheme. We are also committed to providing training and development opportunities including support towards role-related qualifications.
The LMB is a world-class research institute within UK Research and Innovation (UKRI). UKRI is nine research councils, working together across all disciplines and sectors. More information can be found at www.ukri.org and www.mrc-lmb.cam.ac.uk.
Closing date: 03/08/2025
Final appointments will be subject to a pre-employment screening.
We actively support equality, diversity and inclusion in all our activities, processes and culture. We encourage applications from all sections of society. The LMB particularly welcomes women, minority ethnic and disabled candidates to apply for this vacancy as they are currently under-represented. We are a disability inclusive employer and encourage disabled people to apply for this role. You are very welcome to contact us for information about the application process and any adjustments you may require; recruit@mrc-lmb.cam.ac.uk.
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