We are seeking outstanding Postdoctoral Researchers to join a Wellcome Trust Discovery Award–funded project investigating the structural mechanisms underlying genome regulation. The successful candidates will apply cryo-electron microscopy (cryo-EM) and integrative structural biology approaches to study regulatory protein complexes central to genome regulation. The positions are based within a highly collaborative university and research institute environment, offering access to excellent cryo-EM facilities and strong international partnerships. These roles provide an exceptional opportunity to work at the interface of structural biology and genome regulation, addressing fundamental biological questions using cutting-edge methodologies. The position is offered on a fixed-term contract, with the possibility of extension subject to funding. The post holder will benefit from access to outstanding cryo-EM facilities, excellent research support, and an internationally connected research environment. Key responsibilities include Applying cryo-EM and integrative structural biology approaches to study regulatory protein complexes Contribute to experimental design, data analysis, and interpretation Work collaboratively within an international research network Disseminate results through high-quality publications and presentations About you As the ideal applicant, you will have a PhD in structural biology, biophysics, biochemistry, or a related discipline as well as prior experience in cryo-EM. You will be able to demonstrate the ability to conduct independent research as well as s trong communication and teamwork skills. Experience with genome or transcriptional regulation, Computational or integrative modelling experience and pr evious work on multi-protein complexes would be advantageous but not essential. Additional information Informal enquiries are welcome and should be made to Daniel Panne at [email protected] As part of the University’s ongoing commitment to professional development, this role will also be considered on a seconded basis for existing staff members. Please ensure this is discussed with your line manager prior to applying. More information regarding secondments can be found here The University of Leicester has been changing the world, and changing people’s lives, for 100 years. When you join us, you’ll become part of a community of Citizens of Change, which includes not only our staff and our current students but also thousands of Leicester graduates around the world. As a diverse and forward-thinking employer, we embed the principles of equity, diversity and inclusion into everything we do. That includes not just our core missions of teaching and research, but also our support for staff, students and our local community through our values of Inspiring, Impactful and Inclusive through our values of Inspiring, Impactful and Inclusive. We’re committed to the wellbeing of all our staff and to the sustainability of our environment, on our campus and beyond. We offer a competitive salary package, excellent pension scheme and a generous annual leave allowance, along with opportunities to develop your career in a supportive and collaborative environment. Unable to show this video due to your cookie preferences