This position is responsible for leading and managing a small team of Computational Scientists, supporting the Pharmaceutical Development team with a focus on PBPK/PBBM modelling and simulation. This position can offer the opportunity to work on a unique proprietary modelling system which is accelerating clinical drug development.
ROLE OVERVIEW
* Provide scientific and technical leadership and management to a team of Computational Scientists in PBPK
* Lead the execution of client and internal research and development projects in the field of computational pharmaceutics
* To be the recognised point of contact for problem solving in the field of PBPK
* Author and review computational reports for scientific and technical accuracy and to review reports from other teams
* Present results to internal and external stakeholders, including clear communication of technical challenges, in a solution-oriented manner
EDUCATION, EXPERIENCE & RELEVANT SKILLS EDUCATION & QUALIFICATION
* PhD in related discipline with track record of implementing PBPK models in drug development
* Proven experience in software such as GastroPlus, Simcyp, MATLAB or Python to develop and utilise PBBM/PBPK models
* Drug product development using modelling methodologies such as PBPK/PBBM
* Drug product regulation and approval using modelling and simulation tools (i.e. interactions with regulators and authoring of regulatory documents)
* Proven team management experience and working with various stakeholders at different levels across multiple departments
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Created on 22/08/2025 by JR United Kingdom
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