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Research technician

Cottingham
Research technician
£33,002 a year
Posted: 8 May
Offer description

Salary Range: £33,002.00 - £38,784.00 We are committed to equality, diversity and inclusion, creating a community where colleagues feel respected and valued. We aim to reflect the diversity of our students and communities, and to strengthen our university through collaboration and diverse perspectives, across all roles at the University. This job description is currently not available to view while we review and update content on Workday. If you need access to the current version, please submit a request to the People Services Team through the Support Portal. If you need to discuss the job description due to updates to the role or for recruitment purposes, please make this clear on your request and a member of the team will be in touch. Thank you for your patience during this update The Wound Healing team is embedded within the newly established £48M Wound Innovation Institute at the University of Hull, a state-of-the-art translational research facility dedicated to accelerating discoveries in skin wound healing, chronic wounds, and age-related skin conditions toward clinical application. This r esearch project focuses on cellular and molecular mechanisms of skin homeostasis, fibroblast function, senescence, Nrf2 signalling, extracellular matrix remodelling, and therapeutic interventions such as Nrf2 modulation and senolytics. This post will provide essential technical support to a funded 2-year project investigating the roles of Nrf2 in driving pro-healing secretory phenotypes versus senescence in fibroblasts, using integrated in vitro, ex vivo, and in vivo models to identify pathways for enhancing wound repair while preserving long-term skin resilience during aging. The post holder will: Maintain and perform routine primary human skin fibroblast cultures, including treatment with Nrf2 activators or inducible constitutive Nrf2 models. Apply and evaluate senolytic treatments to clear senescent cells, followed by assessment of senescence markers via SA-β-gal staining, qRT - PCR, and immunofluorescence. Collect, prepare, and test conditioned media from treated fibroblasts on normal human epidermal keratinocytes and in ex vivo human skin wound models. Routine histology work including tissue processing, sectioning, and staining/immunofluorescence. The full job description can be found here This role is working 29.2 hours per week (0.8 FTE). The salary stated above is the full time equivalent based on working 36.5 hours per week (1 FTE). For an informal discussion about the role, please contact Paul Hiebert, Lecturer in Wound Healing - P.Hiebert@hull.ac.uk Applications close at 00:01am of the closing date listed. We reserve the right to close this vacancy early if we receive sufficient applications. If you are interested in this role, please submit your application as early as possible.

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