Head of Translational Bioinformatics Immunology - UK
Overview
We are looking for a talented and experienced Translational Bioinformatics Leader who is passionate and agile to join us in our Data Science and Analytics leadership team, based in Slough, UK.
What You’ll Do
* Lead and develop a bioinformatics function with strong ties to local biology and translational functions.
* Define the team’s bioinformatics strategy and contribute to the DSA and overall R&D digital strategy in collaboration with other digital leaders, working closely with other bioinformatics functions across Research.
* Provide scientific leadership, mentorship, and guidance to a team of bioinformatics scientists, fostering a collaborative and innovative work environment.
* Assist UCB’s therapeutic ambitions in neurological diseases by unlocking mechanistic insight from molecular profiling of patient samples, analysing perturbations of patient-derived cell systems and in vivo / ex vivo disease models, and enriching knowledge of disease aetiology to inform new targets and drug mechanism of action.
* Maintain close relationships with focus areas and platform leads as well as with overall research leadership, promoting team capabilities, identifying collaboration opportunities and expanding the team’s impact.
* Initiate and participate in collaborations with external parties, academic, commercial and industry consortia to expand access to human-level data, develop state-of-the-art methods, and provide novel insight, analysis and strategic steer.
* Drive innovation in bioinformatics methods, data visualization, generative and predictive modelling to enhance the impact of data-driven research and help build global bioinformatics tools and data infrastructure, in close collaboration with other Data Science functions.
* Provide authoritative scientific input in drug discovery projects and in scientific governance meetings.
* Embed team members within therapeutic project teams to align bioinformatics efforts with project objectives and communicate insights to influence project decisions and translational packages.
Qualifications
* Ph.D. or equivalent in Bioinformatics, Computational Biology, Immunology, Genomics, or related field with 10+ years of industry experience.
* Proven ability to lead and mentor groups of 5-10 scientists, manage multiple priorities, and foster a collaborative work environment, ideally in pharmaceutical R&D.
* A passion for leveraging bioinformatics to accelerate drug discovery and understanding disease biology, with experience in Immunology insight delivering a qualifying requirement.
* Experience in multi-omics data processing, analysis, and interpretation, with a strong preference for single cell RNA-seq, spatial transcriptomics and methods for integrating genetic data to identify causal biology.
* Experience in supporting translation of drug discovery projects into human clinical trials, enabling pre-clinical assessment, biomarker strategies and back translation.
* Exposure to multiple drug modalities including gene therapy would be a plus.
* Experience with HPC, cloud computing platforms, and containerisation technologies (e.g., Docker) for reproducible and portable bioinformatics workflows. Recent hands-on experience preferred.
About Us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.
Why work with us?
At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work. We go beyond to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. You will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.
EEO
UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities, contact us on EMEA-Reasonable_Accommodation@ucb.com. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
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