Relocation assistance available Join our high-performing Oligonucleotide Production team in Southampton—a vibrant coastal city offering the perfect balance of professional opportunity and quality of life, with excellent transport links. We are seeking a Senior Scientist with deep expertise in downstream processing modalities including oligonucleotides/Peptides to lead analytical strategy and contribute to the development and production of high-quality modified Oligonucleotides Key responsibilities Lead and oversee downstream workflows, supporting purification, analysis and characterisation of oligonucleotides including HPLC, SDS-PAGE, TFF and UPPL-MS Stay abreast of emerging technologies and methodologies in nucleic acid chemistry Drive method development and troubleshooting with purification techniques Ensure rigorous documentation Collaborate cross functionally across the organisation Coach and mentor junior team members Skills and Experience PhD in Chemistry and/or related discipline Proven hands-on experience working with oligonucleotides/peptides is highly desirable within Academia or Industry (Small molecule experience will also be considered) Experience of UF/DF and TFF is highly desirable Strong background in purification and downstream processing techniques - HPLC, UPLC-MS, SDS-PAGE Experience working in ISO/GMP regulated environments is highly desirable Self-starter with the ability to lead projects which require troubleshooting and problem solving Detail orientated, strong communicator who can work under pressure in a fast-changing environment What we can offer you: 25 days annual leave plus 8 paid bank holidays Contributory pension scheme (6% employer contribution) Flexible working hours Life Assurance (x4 salary) Long service awards Reward and recognition scheme Employer Assistance Programme with 24/7 remote GP service Annual flu jabs Cycle to work scheme Corporate discount on gym membership Savings and discounts Reimbursement of professional membership fees Referral incentives Social events Volunteering days Biotage is a global supplier and solutions partner to a wide range of customers within drug discovery and development and analytical testing. With strong expertise in separation and purification technologies, and a focus on leveraging intelligent workflow solutions, we aim to efficiently support the advancement and protection of human health. Learn more at biotage.com