Job title: Director, Clinical Immunology Job type: Full-time Location: Oxford / hybrid working arrangements Salary: Competitive salary Deadline: 29th May 2026 Application submission: CV and cover letter via our website www.omass.com/working-here/ OMass Therapeutics is a biotechnology company based in Oxford discovering medicines against highly- validated target ecosystems, such as membrane proteins or intracellular complexes. The company’s unique OdyssION™ technology platform comprises novel biochemistry techniques, next-generation native mass spectrometry, and custom chemistry. OMass is advancing a pipeline of small-molecule therapeutics in rare diseases and immunological conditions that target solute carriers, complex-bound proteins, and GPCRs. We are seeking a Clinical Immunologist to join our team. You will be part of a dynamic, innovative environment and become an integral part of our vision to address patients’ unmet needs while building Britain’s Biggest Biotech. You will provide internal and external-facing immunology clinical development expertise and leadership for the OMass immunology portfolio, reporting to the VP, Clinical Development, and collaborating with a focused and caring team. Discover the impactful work OMass delivers and explore our Employee Value Proposition here https://www.omass.com/working-here. Role Overview • Partner with the Translational Pharmacology team to shape and deliver the company’s immunology strategy to develop a portfolio of differentiated and commercially viable immunology assets • Lead clinical development strategy, planning and execution for OMass pipeline of first-in-class immunology assets • Contribute to discovery and pre-clinical plans to deliver development candidates with highly differentiated target product profiles • Drive efforts to establish clinical biomarker plans to demonstrate early proof-of-mechanism and value generation for early immunology assets • Contribute to target identification and selection activities, including patient stratification strategies Essential Experience, Skills and Qualities • MD or MD/PhD with significant experience in immunology and drug development, and a strong track record of advancing novel immunology drug candidates through clinical trials, preferably in a biotech setting • Industry recognition as a subject matter expert and extensive knowledge of immunology, particularly in autoimmune diseases • Experience in designing and overseeing clinical trials, including familiarity with regulatory requirements • Strong communication and interpersonal skills, with the ability to collaborate across multi-functional teams • Strong presentation skills with the ability to present at Board level and to external stakeholders with credibility and confidence • Strategic thinking capabilities and the ability to identify and solve complex problems Role Responsibilities • Lead all aspects of clinical development planning from phase 1 to registration with a multidisciplinary team for immunology assets, rapidly and efficiently maximising candidate molecule potential and differentiation with scientific rigour, and delivering critical data required to make decisions at each key milestone • Lead a cross-functional clinical trial team to design and execute high-quality, innovative clinical studies within governance-approved timeline and budget commitments, collaborating effectively with internal colleagues and external partners • Collaborate with discovery and preclinical teams to develop and deliver insightful translational plans • Responsible for presentation of results and updates of projects at project, corporate and scientific meetings • Establish and manage relationships with key opinion leaders and patient organisations to gain and incorporate insights to inform clinical strategy and operational decisions • Engage in clinical development support across the portfolio • Support Business Development, including due diligence activities OMass Benefits OMass offers an excellent benefits package, including: • Private Health Insurance • Health and well-being cashback scheme • Life Assurance and Income Protection • Participation in Employee Equity Scheme • 25 days annual leave, plus bank holidays • Pension Scheme offering 6% employer contribution • Learning and Development Opportunities • Company social events Any queries relating to the role can be sent to hr@omass.com. OMass Therapeutics values diversity and is committed to equality of opportunity. We also have a responsibility to ensure that all employees are eligible to work and live in the UK.