Postdoctoral Research Scientist - Neuronal Cell Biology, Oxford
Client: University of Oxford
Location: Oxford, United Kingdom
Job Category: Other
EU work permit required: Yes
Job Reference:
Job Views: 5
Posted: 02.06.2025
Expiry Date: 17.07.2025
Job Description:
We are seeking a Postdoctoral Research Scientist (Neuronal Cell Biology) to join the Wade-Martins Laboratory at the Kavli Institute of Nanoscience Discovery within DPAG. The ideal candidate will be a neuronal cell biologist with experience working in neuronal models of neurodegeneration, ideally in human stem cell-derived models, and a good knowledge of Parkinson’s disease. In this role, you will differentiate iPSC-dopamine neurons from Parkinson’s patients and controls to target the pathological protein alpha-synuclein. You will treat neurons with peptides targeting alpha-synuclein and use cellular assays to test for alleviation of protein pathology and disease phenotypes. This post is available immediately until 31 August 2027.
Key responsibilities:
* Undertake analysis of the phenotypic effect of treating neurons with peptides targeting alpha-synuclein on cell biology phenotypes in cellular models of Parkinson’s.
* Manage own academic research and administrative activities, including small-scale project management to meet deadlines.
* Contribute ideas for new research projects.
* Develop ideas for generating research income and present detailed research proposals to senior researchers.
* Collaborate in the preparation of scientific reports and journal articles, and occasionally present papers and posters.
Selection criteria:
* Hold, or be close to completion of, a PhD/DPhil in molecular and cellular neuroscience, or equivalent.
* Knowledge of the cell and molecular biology mechanisms of Parkinson’s disease, or related neurodegenerative conditions.
* Experience in neuronal cell culture, preferably in human pluripotent stem cells.
* Experience in setting up cellular assays and techniques in cell and molecular neuroscience.
What we offer:
Your wellbeing at work matters, so we offer a range of family-friendly and financial benefits including:
* An excellent contributory pension scheme
* 38 days annual leave
* A comprehensive range of childcare services
* Family leave schemes
* Cycle and electric car loan schemes
* Employee Assistance Programme
* Membership to social and sports clubs
* Discounted bus travel and Season Ticket travel loans
While this is a full-time role, we welcome applications from individuals who wish to be considered for flexible working arrangements.
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