About the Job
Northreach is a specialist life science recruitment partner, connecting pioneering biotech and biopharma companies with exceptional scientific talent. We partner with businesses that are shaping the future of medicine and empower candidates to take the next step in their scientific careers.
One of our innovative biotech clients is seeking a Senior RA/Scientist – CAR-T Cell Therapy to join their growing R&D team in Oxford, UK. This full-time, permanent position offers the opportunity to contribute to the development of next-generation CAR-T cell therapies designed to tackle solid tumours and other high-value oncology indications.
The ideal candidate will have recently completed a PhD in CAR-T research, immuno-oncology, or a related field and will be eager to apply their academic expertise to real-world therapeutic development in a dynamic, fast-paced environment.
The Role
* Design and execute in vitro functional assays (e.g. cytotoxicity, cytokine release, proliferation) to assess CAR-T activity.
* Culture and expand primary human T cells using aseptic techniques.
* Develop and validate flow cytometry panels for immunophenotyping.
* Support high-throughput screening of CAR constructs for potency and specificity.
* Maintain detailed electronic lab records and ensure data integrity.
* Analyse and present results to cross-functional R&D teams.
* Collaborate with scientists and engineers across discovery, translational, and process development functions.
* Contribute to lab operations, SOP development, and mentoring of junior staff.
The Profile
* PhD in Immunology, Cell Biology, or related field with research focused on CAR-T, T cell engineering, or immuno-oncology.
* Hands-on experience with mammalian cell culture and immunological assays.
* Skilled in flow cytometry and data analysis tools (FlowJo, GraphPad Prism).
* Strong experimental design, troubleshooting, and analytical skills.
* Excellent communicator with meticulous attention to detail.
1. Why Apply
This is an exceptional opportunity for a recently qualified PhD scientist to translate cutting-edge CAR-T research into meaningful clinical applications. You’ll join a pioneering biotech at the forefront of cell therapy innovation, working alongside world-class scientists to help shape the next generation of cancer immunotherapies.