Senior / Lead Clinical Research Associate | Global CRO | UK (Home-Based)
Are you a seasoned CRA looking to transition away from high-volume, repetitive studies toward more intricate, high-science clinical trials?
Our client is a global leader in clinical research, consistently recognised for its patient-centric approach and an industry-leading pipeline of complex therapies. They are currently seeking experienced Senior and Lead CRAs across the UK to oversee diverse portfolios, ranging from early-phase oncology to rare disease and advanced medicinal products.
The Role
As a Senior or Lead CRA, you will act as the primary liaison between the sponsor and investigative sites. This is not a \"checklist\" monitoring role; it requires a mindset to manage site relationships and navigate the nuances of sophisticated protocols.
Key Responsibilities:
* Independent Monitoring: Conduct initiation, routine monitoring, and close-out visits for complex, multi-centre trials.
* Site Management: Drive recruitment strategies and provide expert guidance to site staff on protocol-specific requirements.
* Leadership & Mentoring: (Lead level) Provide oversight to junior CRAs, lead project initiatives, and act as a point of clinical escalation.
* Quality & Compliance: Ensure all activities adhere to ICH-GCP, local UK regulations, and rigorous internal SOPs.
Why This Organisation?
This company distinguishes itself through a genuine commitment to the patient experience, ensuring that trial designs are accessible and ethical.
* Therapeutic Complexity: You will work on \"cutting-edge\" science, including gene therapies and immuno-oncology, rather than standard biosimilar or primary care studies.
* Empowered Autonomy: While you benefit from a global infrastructure, you are trusted to manage your own schedule and site relationships.
* Career Progression: A transparent promotion structure allows for transitions into Project Management, Line Management, or Clinical Trial Management.
* Work-Life Balance: They offer a sensible monitoring model to reduce excessive travel and maintain a healthy home life.
Candidate Requirements
We are looking for clinical professionals who take pride in the quality of their data and the strength of their site partnerships.
* Experience: A minimum of 3+ years of independent monitoring experience within the UK (CRO or Pharma).
* Education: A life sciences degree or a nursing background is essential.
* Technical Proficiency: Extensive knowledge of ICH-GCP and the UK regulatory environment.
* Soft Skills: Exceptional communication skills and the ability to influence stakeholders at all levels.
* Mobility: A valid UK driving licence and the flexibility to travel to sites nationwide as required.
Remuneration & Benefits
* Competitive Salary: £55,000 – £62,000 (dependent on experience and level).
* Car Allowance: Significant monthly allowance or company car options.
* Performance Bonus: Annual incentive scheme based on quality and company performance.
* Flexible Benefits: Private healthcare, enhanced pension scheme allowance.
To Apply: If you are ready to apply your expertise to more challenging therapies within a supportive, global environment, please submit your CV for a confidential discussion to