Company Overview
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated and cured. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for humanity. Learn more at jnj.com.
We are guided by our Credo and provide an inclusive work environment where each person is considered an individual. We respect diversity and recognize merit.
Job Title
Senior Local Trial Manager (Senior LTM)
Job Function
R&D Operations
Job Sub Function
Clinical Trial Project Management
Job Category
Professional
Location
High Wycombe, Buckinghamshire, United Kingdom (moving to Maidenhead October 2026). This position is hybrid, requiring 3 days per week on-site.
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science‑based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine
Purpose
The Senior LTM is the primary point of contact at the country level for assigned studies and has operational oversight of assigned protocols from start‑up through to database lock and closeout activities. He/she is responsible for proactively coordinating and leading the local trial team to deliver quality data and trial documents/records that are compliant with the assigned clinical trial protocol, company SOPs, GCP, and regulatory standards. The Senior LTM will also actively contribute to process improvement, training and mentoring of Clinical Trial Assistant (CTA) and Site Manager (SM) roles, and may have some site management responsibilities.
Responsibilities
- Collaborate with the Manager, Clinical Operations (MCO) for country protocol and site feasibility assessments, ensuring consistent and high quality conduct of site qualification visits and country feasibility reports; recommend suitable sites for selection and set predictable and realistic start‑up timelines.
- Lead and coordinate trial activities in compliance with SOPs, other procedural documents and regulations; lead local project planning activities to meet recruitment targets and deliver high quality data on time and within budget.
- Act as the subject matter expert for assigned protocols and develop strong therapeutic knowledge.
- Act as primary country contact for a trial, establishing and maintaining excellent working relationships with external organisations, investigators, study coordinators and site staff; and with internal partners, including Medical Affairs.
- Maintain and update trial management systems using available study tools and management reports to analyse trial progress.
- Monitor country progress, initiate Corrective and Preventive Actions when the trial deviates from plan, identify and resolve issues, and communicate study progress and issues to local and global study management teams.
- Review and approve Monitoring Visit Reports submitted by Site Managers, identify issues and trends across a trial project.
- Prepare IRAS submissions and be responsible for approvals during the trial.
Qualifications / Requirements
- BA or BSc degree in Life Sciences, Nursing or a related scientific field (or equivalent experience) is required.
- A minimum of 3 years of UK clinical trial experience is preferred; experience managing Oncology studies is an advantage.
- A minimum of 1 year of demonstrable Project Management experience is required.
- Proven understanding of the drug development process, including GCP and local regulatory requirements.
- Proficiency in spoken and written English.
- Excellent written and oral communication skills.
- Strong leadership skills and demonstrated ability to lead initiatives or small teams.
- Ability to work on multiple trials in parallel, if required.
- Flexibility to commute 3 days per week to the High Wycombe or Maidenhead office.
Benefits
We offer a competitive salary and extensive benefits package. The health and well‑being of our employees is a priority, and we maintain a flexible working environment to support work‑life balance. Career development opportunities are available for those who wish to grow within our organization.
EEO Statement
Johnson & Johnson Family of Companies are equal‑opportunity employers, and all qualified applicants will be considered for employment without regard to any other characteristic protected by law. We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Required Skills
- Clinical Trial Management
- Good Clinical Practice (GCP)
- Project Management
- Team Mentoring
Preferred Skills
- Business Behavior
- Clinical Research and Regulations
- Clinical Trial Designs
- Clinical Trial Management Systems (CTMS)
- Clinical Trials
- Communication
- Give Feedback
- Laboratory Operations
- Medical Knowledge
- Mentorship
- Oncology
- Problem Solving
- Process Oriented
- Professional Ethics
- Project Integration Management
- Research and Development
- Research Ethics
