Job Description
Scientist Analytical Development & Validation - Oxford Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company dedicated to developing transformative medicines for unmet patient needs in oncology, infectious diseases, and autoimmune diseases. Our R&D leaders are internationally recognized as some of the biotech industry's most successful drug developers. We foster an environment where collaboration, innovation, and scientific excellence thrive.
Our focus is on delivering first-in-class biological therapies. We have developed an innovative soluble TCR platform and ImmTAX molecules that harness the immune system to treat a broad spectrum of diseases. At Immunocore, our employees are our greatest asset, and we are committed to an inclusive workplace that values diversity and equal opportunity.
We encourage applications from individuals of all backgrounds. Successful candidates will join a dynamic team developing analytical methods to support our expanding pipeline of biopharmaceuticals. The core responsibilities include developing and transferring chromatography and electrophoresis-based methods for lot release and stability testing, and providing analytical expertise for program development both internally and with CDMO partners.
Key Responsibilities:
1. Developing and qualifying UHPLC and gel/capillary electrophoresis methods for stability, lot release, and characterization testing.
2. Evaluating novel analytical techniques for platform development.
3. Contributing to method transfer to CDMOs.
4. Designing and conducting experimental investigations with guidance.
5. Preparing and reviewing study protocols and reports.
Additional Responsibilities:
* Planning experiments and adhering to deadlines.
* Sharing technical knowledge and skills with colleagues.
* Maintaining accurate laboratory records.
* Training on technical instruments and using equipment appropriately.
* Communicating research findings effectively.
* Following safety policies in laboratories.
Person Specification
Experience & Knowledge (Essential):
* At least 2 years of industry experience in recombinant protein or antibody/biopharmaceutical analytical development or QC.
* Hands-on expertise with HPLC/UHPLC techniques for protein analysis.
* Experience with electrophoretic methods such as CE-SDS.
* Knowledge of assay qualification/validation and GMP principles.
* Strong record-keeping and self-learning abilities.
Desirable:
* Experience with imaging capillary IEF, Western blotting, mass spectrometry.
* Understanding of stability studies and method transfer.
* Experience presenting scientific results.
Education & Qualifications:
* Essential: BSc or MSc in biochemistry, biotechnology, or related discipline.
* Desirable: PhD in a related discipline.
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