We are seeking
to appoint a well-trained, enthusiastic and self-motivated scientist to join our team to investigate the mechanisms underlying the function of non-canonical RNA / DNA structures (R-loops) in health and diseases. The post-holder will be responsible for managing their own academic research. The research project will involve a wide range of molecular biology and biochemical techniques, including RNA work, protein purification, mammalian cell culture, next generation sequencing genome-wide analyses (ChIP) and mass spectrometry. You will establish and optimise protocols, design and accurately execute experiments and contribute conceptually to the overall research programme. The post-holder should hold, or be close to completion of, a PhD / DPhil in biochemistry, molecular / cell biology or genetics. You should have a good understanding of the principals of gene expression in higher eukaryotes as well as prior experience in biochemistry, molecular / cellular biology. You should have expertise in either molecular mechanisms of transcription, RNA biology, DNA damage or R-loop biology. Strong publication record, excellent organisational and communication skills are essential. Candidates with experience in genomic analyses, proteomic approaches, imaging analysis, iPS differentiation and bioinformatics would be especially welcome.
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