Overview
Senior Scientist - Bioscience Renal in vivo (Maternity cover)
Join to apply for the Senior Scientist - Bioscience Renal in vivo (Maternity cover) role at AstraZeneca.
Are you ready to turn ideas into life-changing medicines? At AstraZeneca, we are driven by the potential of science to address unmet patient needs globally. Our vision is to push the boundaries of science, redefining the practice of medicine and ultimately eliminating diseases like cancer, respiratory, cardiovascular, and renal conditions. This vivarium-based role is in the Animal Sciences & Technologies (AST) Department in Cambridge, where pivotal studies evaluate drug efficacy, safety, and pharmacokinetics. Use your expertise to collaborate with disease-focused teams and support the growth of our drug portfolio.
Introduction To Role
At AstraZeneca, we are led by science and driven by patients. It’s at the heart of our every success. This role is a Senior Scientist with knowledge in in vivo experimental biology to join the Bioscience Renal in vivo team within the Early Cardiovascular, Renal and Metabolism (CVRM) therapeutic area. The position is placed at AstraZeneca’s R&D site in Cambridge, UK.
As a Senior Scientist in the Early CVRM Renal department at AstraZeneca, you will be part of a team that focuses on finding new treatment options for patients with renal disease. In the in vivo team, we work with various pre-clinical models and different drug modalities. You will conduct experimental studies, develop renal in vivo models, and perform biomarker analysis to drive our targets. You will work with experts from different functions and be part of project teams.
Responsibilities
Accountabilities
* Independently develop, plan and perform high quality in vivo experiments in rodent models of renal disease
* Investigate MoA
* Perform Ex vivo analyses of fluids and tissue for biomarker quantification
* Identify and implement new models/assays relevant for renal disease area
* Act as Bioscience representative in projects
* Analyse and deliver data, presentations, reports and regulatory documents in a timely manner
* Ensure that own work and work with others is performed according with appropriate safety, health and environment (SHE), qualify and compliance standards, e.g. General Laboratory Standard (GLS)
Essential Skills/Experience
Essential Skills/Experience
* Experienced hands on in vivo biologist with a PhD or equivalent experience (or MSc with 3+ years or BS with 5+ years in vivo experience in industry or academic setting) in biology, physiology, pathology or medicine or other relevant area
* Extensive expertise in running in vivo experiments in rodents
* Excellent experimental skills in the use of in vivo techniques and good understanding of animal handling and care
* Ex vivo, in vitro techniques - qPCR, ELISAs etc
* Flexibility & independence
* Educated and certified for in vivo experimentation
* Strong oral and written communication skills in English
Desirable Skills/Experience
Desirable Skills/Experience
* Holder of UK Home Office Personal Licence
* Experience in renal models
* Experience in biomarker identification in body fluids and tissues
* Expertise in renal physiology and/or pathology
* Experience from Pharmaceutical industry
What’s next?
What’s next?
Are you already envisioning yourself joining our team? Good, because we can’t wait to hear from you!
To Find Out More
Group site: https://www.astrazeneca.com/
Our social media, Follow us on LinkedIn: AstraZeneca
Inclusion & Diversity: https://careers.astrazeneca.com/inclusion-diversity
Career site: https://careers.astrazeneca.com/
Date Posted: 07-out.-2025
Closing Date: 20-out.-2025
Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
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