Overview:
Aviceda Glycotech located in Belfast, Ireland, a wholly owned subsidiary of Aviceda Therapeutics, is seeking an entrepreneurial, strategic, driven, and visionary scientific Consultant to join our team as Sr. Director/VP, Biology and Translational Research. The person will serve as a critical part R&D Leadership Team, working towards building a discovery oncology and immunology pipelines to develop best-in-class medicines and new modalities. The person will work with biology and translational research team(s) through state-of-the-art scientific innovation, strategy, and operations to continuously develop and expand the technology platform leading to new clinical candidates.
Summary of Key Responsibilities:
* Lead consultant to a discovery biology & translational team - responsible for the oncology/immunology target identification, discovery, and pre-clinical development leading to new clinical candidates.
* Direct the creation of enabling various in vitro assays and help with in vivo models and pharmacology experiments in support of program objectives
* Provide creative and innovative leadership of discovery biology enabling biological hypotheses into transformative medicines.
* Ensure effective interaction and communication between Biology and Chemistry teams, in alignment with the leadership team.
* Communicating discovery strategy and progress to executive management, scientific board of directors, and external partners.
* Expand the company's external network of advisors and establish deep domain area expertise in program areas such as immunology/inflammation, and oncology.
* Keep up to date with the latest scientific advances, technologies, and trends in oncology, immunology research, and development to deliver the next generation of therapies.
* Advancement of research programs to support corporate growth goals.
* Cross-functional collaboration with Regulatory to author strategy for first in human studies.
* Develop key internal and external stakeholder collaborations.
* Work with teams responsible for designing and executing early clinical programs.
* Contributions in cross-functional setting Identify therapeutic targets, disease mapping and pipeline strategy
* Establishing and maintaining collaborative relationships with internal functional groups (e.g. Discovery, Clinical, CDTs), external academic research groups and CRO’s to facilitate the implementation of research strategies in Clinical trials.
* Assimilate advancement of early studies into the assessment of risk and investment in programs.
* Regular interactions with senior leaders to align development goals with functional and corporate initiatives
Qualifications:
* A proven scientific leader with a Ph.D. in Biology/Biochemistry/Cell Biology
* 10 to 15+ years of biotechnology and pharmaceutical drug discovery R&D experience
* Demonstrated expertise and a track record of success in advancing discovery programs from target validation through lead optimization and into clinical development.
* Track record of target discovery and validation, cell biology, assay and model development, biomarkers across therapeutic areas and target classes. Strong focus on using new cutting-edge technologies to drive new, deep mechanistic insights into disease biology.
* Therapeutic domain expertise in immunology and oncology
* Extensive experience in CRO management of drug discovery programs
* A highly engaged, self-starter who is creative, proactive, innovative, and communicative and possesses both a collaborative and goal/results-oriented style.
* A track record of effectively communicating scientific concepts and strategies, including publication records in top-tier, peer-reviewed journals.
* Very strong communication and partnering skills including identification of new collaboration opportunities and conduct through diligence
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