The role
The University of Bristol is seeking a Research Associate to work with Dr Ben Faber on a Wellcome Trust-funded project entitled ‘Utilising large joint structural phenotypes of osteoarthritis for enhanced disease prediction and novel treatment target discovery.’The primary aim is to leverage imaging and genetics to identify novel treatment targets for osteoarthritis. Applicants are sought who have experience with UK Biobank imaging data and epidemiological skills.
What will you be doing?
* The successful candidate will work extensively with UK Biobank dual-energy X-ray absorptiometry scans in UK Biobank.
* They will be expected to be adept at analysing hip and knee images to obtain accurate measures of joint shape and radiographic osteoarthritis.
* They will be expected to be able to use advanced coding methods in Python, R and Stata to develop and curate a data set of over 240,000 scans across 70,000 individuals.
* Epidemiological analyses will be used to identify novel relationships between structural phenotypes of osteoarthritis and clinical outcomes.
* Genetic epidemiology will be used to conduct genome-wide association studies of imaging features of osteoarthritis.
You should apply if
* Considerable experience (> 1 year) of analysing UK Biobank DXA imaging data
* Proficient at using Statistical Software e.g. Stata, R, Python
* Experienced at analysing Hospital Episode Statistic data and other forms of electronic healthcare records (e.g. OPCS3 & OPCS4)
* In depth understanding of osteoarthritis and risk factors for disease
* Experienced at handling and curating large datasets
* Well organised and able to work to independently
* Ability to identify technical problems, in collaboration with the project’s PIs, and discuss to identify solutions
* Track record of collaborating across institutions to deliver complex research projects
* Publications in the field
Additional information
Contract type: Open-ended with 3 years of funding from the start date
This advert will closeat23:59 UK timeon 08/07/2025
For informal queries please contact:Ben Faber –ben.faber@bristol.ac.uk
Our strategy and mission
We recently launched ourstrategyto 2030 tying together our mission, vision and values.
The University of Bristol aims to be a place where everyone feels able to be themselves and do their best in aninclusive working environment where all colleagues can thrive and reach their full potential.We wantto attract, develop, and retain individualswith different experiences, backgrounds and perspectives – particularly people of colour, LGBT+ and disabled people - because diversity of people and ideas remains integral to our excellence as a global civic institution.
Available documents
* Faculty of Health and Life Sciences - October 2024.pdf
* Bristol Medical School - October 2023.pdf
* ACAD108168 - RA in Image Analysis, Big Data and Epidemiology JD.pdf
£38,249 to £44,128. Grade I / Pathway 2, per annum
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