Senior Scientist - Assay Development & High-throughput Screening | FTC 7 months
Location: Oxford, UK
Responsibilities
The primary purpose of this role is to leverage a strong working knowledge of biologics assay development and high-throughput screening to solve day‑to‑day problems while developing expertise in related areas.
The role involves responsibility for developing and implementing high throughput, automated cell assays for the discovery of transformative T cell engager medicines. In addition to identifying and building innovative, state‑of‑the‑art assays to identify and assess the functional properties of potential candidate therapeutics, the role will involve liaising with Drug Discovery and automation scientists to streamline drug discovery.
* Independently identify, design, develop, and validate state‑of‑the‑art cell assays for assessment of target binding and functional properties of T cell engager molecules.
* Work alongside automation experts to build, optimise and implement high‑throughput cell binding assay capabilities.
* Analyse, interpret and effectively communicate experimental results, recommendations and plans to project teams.
* Maintain a good understanding of state‑of‑the‑art and emerging biologics drug formats and the assays used for characterisation.
* Contribute to identifying, evaluating, building, and applying innovative cell assays and streamlining drug discovery processes.
* Troubleshoot and identify resourceful, relevant solutions for complex scientific challenges.
* Contribute to internal and external collaborations.
* Provide technical training to team members where required.
* Follow Good Laboratory Practice and adhere to Immunocore health and safety policies.
Education and Experience
Essential Qualifications
* Normally requires a PhD in a scientific discipline and a minimum of 2‑5 years related experience; may include post‑doctoral experience.
* Or MSc degree or BSc degree with extensive role‑specific equivalent research or industrial experience.
Essential Experience, Knowledge & Abilities
* Experienced in performing biologics assays.
* Experienced in use of automation e.g. liquid handlers.
* Experienced in use of functional cell assays for biologics.
* Track record of solving scientific problems creatively.
* Track record of collaborating and contributing as a project team member.
* Effective communication of scientific concepts and findings.
Preferred Experience, Knowledge & Abilities
* Experience in scripting and troubleshooting of automation systems.
* Experience with high‑throughput screening methodologies.
* Experience in biologics drug discovery.
* Track record of evaluating innovative solutions to improve processes.
Other
* Attention to detail and quality.
* Strong organisation skills with ability to plan, prioritise and coordinate work with others.
* Strong team player with ability to actively listen and work productively with other team members in a matrix environment.
* Ability to communicate clearly to relevant audiences.
* Demonstrates innovative thinking.
About the Company
Immunocore (NASDAQ: IMCR) is a pioneering, commercial‑stage T cell receptor biotechnology company whose purpose is to develop and commercialise a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first‑in‑class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognise that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, colour, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.
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