Job Description
CK Group is recruiting for an experienced and dynamic Scientist, at either Senior or Principal level, to join an early-stage biotechnology start-up based in Oxford on a permanent basis.
The Company:
Our client is an early-stage biotechnology start-up combining artificial intelligence (AI) and advanced high-throughput TCR screening techniques to revolutionise the treatment of solid cancers.
Location:
Oxford.
The Role:
To lead the in vivo and in vitro validation of T-cell engagers, and help drive the development of TCR engineering and processes.
Responsibilities:
* Perform high-throughput TCR display methods by purifying recombinant TCRs.
* Carry out protein characterisation (expression, purification, and biophysical analysis).
* Design and characterise TCRs for disease targets.
* Oversee lab protocols and technical documents.
* Be hands-on in the lab and manage tissue culture preparations.
Skills:
Skills in data analysis (using software R) for Next Gen Sequencing analysis are desirable.
Your Background:
* PhD qualified in biochemistry, immunology, or cell biology, with strong laboratory experience (academia and industry).
* Experience in in vivo and in vitro validation of T-cell engagers (TCEs).
* Experience with Investigational New Drug (IND) enabling/approval is ESSENTIAL.
* Expertise in cell and immunological assays (flow cytometry, ELISA) with knowledge of cloning and PCR.
* Strong background in protein and biophysical characterisation.
Benefits:
Competitive salary, option for home working (as per project demands), stock options.
Apply:
It is essential that applicants hold entitlement to work in the UK. Please quote the job reference (Apply online only) in all correspondence.
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