Applications are invited for a Research Associate position in Dr Maria Rostovskaya's group at the Gurdon Institute, University of Cambridge. This position is funded by a Medical Research Council Career Development Award to Dr Rostovskaya.
Our lab investigates the molecular and epigenetic mechanisms that regulate cell fate decisions during early human development, with a focus on timing and order. We combine human pluripotent stem cell-based models of early development with targeted genetic and epigenetic perturbations, genomics, single‑cell molecular analyses, and computational modelling to uncover the principles guiding human embryogenesis. For more information about the laboratory: https://www.gurdon.cam.ac.uk/people/maria-rostovskaya/
Responsibilities
* Lead a project investigating the molecular and epigenetic control of lineage specification using human pluripotent stem cells.
* Apply advanced wet‑lab methods, including stem cell‑based models, chromatin biochemistry, CRISPR‑based genetic and epigenetic editing tools, high‑throughput sequencing.
* Perform bioinformatic analysis of genomics data.
* Develop experimental approaches to edit epigenetic states of regulatory elements.
Qualifications
* PhD in stem cell biology, developmental biology, or related discipline (or soon to be awarded).
* Strong interest in developmental mechanisms, lineage specification, and epigenetic gene regulation.
* Experience in stem cell and developmental biology (required); experience in computational genomics (advantage).
* Recent first‑author research publications or preprints (within the past two years) highly desirable.
* Excellent scholarly outputs and communication skills.
* Ability to work independently and as part of a team.
* Articulate career vision in cover letter.
Terms
Fixed‑term: The funds for this post are available for 3 years in the first instance.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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