Associate Director, Signal Detection Scientist
* Job title: Associate Director, Signal Detection Scientist
* Function: Product Safety
* Sub function: Pharmacovigilance
* Category: Senior Principal Scientist, Pharmacovigilance (ST8)
* Location: High Wycombe, Buckinghamshire, United Kingdom
* Date posted: Oct 31 2025
* Requisition number: R-032672
* Work pattern: Hybrid Work
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com
Job Description
The objective of this position is to lead the implementation of the Signal Management Group aggregate surveillance strategies for proactive and systematic detection and evaluation of new safety signals and emerging trends from post‑marketing safety data for complex pharmaceutical products (e.g., large innovative programs, new therapeutic areas, or complex business partner relationships). The role includes development, evaluation, piloting, and use of novel, computer‑assistant tools and methodologies for signal detection and analysis of internal company safety data, international regulatory safety databases, and other data sources such as claims and electronic medical records.
The position develops and implements product‑specific surveillance plans, performs post‑marketing signal detection activities, including signal validation, and participates in communication of emerging signals in forums such as the Product Team Meetings and Safety Management Team Meetings. It also contributes to strategy development for signal evaluation, guidance on data sources and analysis methods, and may support activities such as ad hoc data mining of FDA FAERS, WHO VigiBase, and EMA EudraVigilance databases. The role supports exploration of new signal detection methodologies, tools, and data sources to further the science of safety surveillance.
Primary Responsibilities
* Identify and assess (validate) new safety signals and trends by conducting systematic reviews of aggregate data with a focus on spontaneous adverse event reports, including system‑wide and ad hoc data mining in Empirica Signal.
* Prepare reviews of topics and summary analysis reports of safety data, with minimal guidance.
* Provide recommendations for further signal evaluation.
* Work with key customers and business partners (Medical Safety Officers, Safety Scientists, and other Safety Physicians) in developing and implementing product‑specific surveillance plans.
* Participate as member of matrix teams to address product‑specific safety issues, assist in the development of signal evaluation strategies, and participate in signal evaluation.
* Communicate findings from routine and ad hoc signal detection and assessment activities.
* Assist in the development and implementation of programmatic surveillance of adverse event reports for potential safety and product quality issues.
* Assist in the evaluation of novel, computer‑assistant tools and methodologies for analysis of safety data, including piloting new data sources and methodologies.
Qualifications
Education:
* Bachelor’s Degree required.
* Advanced Healthcare‑related Degree (e.g., RN, BSN, PharmD) with 3+ years industry experience in drug safety or related area and 1+ year of clinical/patient‑care experience highly preferred.
Required:
* Understanding of global health authority regulations and guidance surrounding the processing, reporting and evaluation of adverse events.
* Experience in single‑case medical assessment, post‑marketing aggregate adverse event data reviews, evaluation of drug safety issues, adverse event dictionaries, core labeling, and Periodic Safety Review preparation.
* Ability to lead projects.
* Skillful in presenting complex data in a concise and understandable scientific manner.
* Ability to thrive in a global, matrix environment – able to handle high workload and critical issues.
* Up to 10% travel – Domestic & International.
Preferred:
* Ability to manipulate data in platforms such as Excel and SAS JMP.
* Familiarity with applied epidemiologic principles of case series evaluation and understanding of computer‑assistant methodologies for safety data analysis.
* Knowledge in public health surveillance and tools (relevant work experience or Masters Public Health or equivalent).
* Knowledge of statistics, system analytics, information systems engineering, or machine learning.
Additional Information
Discovery & Pre‑Clinical/Clinical Development: Learn about working at J&J in our locations across Europe, the Middle East and Africa.
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