Medical Director, Clinical Development, Respiratory
GSK is seeking a Medical Director, Clinical Development, Respiratory to provide clinical and scientific insights to potential new, established and emerging assets in clinical development with a strong focus on respiratory disease. You will work within project teams to plan, execute, and deliver clinical development activities and support medical governance up to and including registrational studies. This role is pivotal in driving GSK’s mission to deliver transformative medicines to patients, ensuring clinical excellence, regulatory compliance, and operational efficiency.
About RIIRU
The Respiratory, Immunology and Inflammation Research Unit (RIIRU) was formed in 2024 to identify and advance novel molecular targets with genetic associations to disease based on the foundational observation that targets with human genetic evidence supporting their causal role in the intended indication improves clinical success by two-fold. The remit of RIIRU is to identify novel targets, develop assets for clinical studies, and perform trials through to submission for approvals, enabled through strategic external and GSK‑internal partnerships.
PLEASE NOTE: This career opportunity requires an on‑site office presence (minimum of two days a week) at one of GSK’s US (PA or MA) or UK (Stevenage or London HQ) sites.
Key Responsibilities
* Contribute to project team discussions on indication planning and incorporate input from across disciplines to support vital deliverables including the Target Medicine Profile (TMP), clinical development plan (CDP), study protocols, and integrated evidence strategy (IES) and planning.
* Provide effective support to the development and execution of the IES, including oversight of R&D evidence generation activities to ensure patient safety and study delivery.
* Design and execute clinical development plans across advanced stages of development, reflecting internal and external stakeholder input.
* Contribute to ambitious clinical development timelines by overseeing development of clinical study protocols, amendments, investigator brochures, clinical study reports, etc.
* Input to, and may lead, regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs.
* Provide medical monitoring and oversight of the safety of study participants.
* Act as clinical lead for a study, serving as clinical point of contact on the Clinical Matrix Team (CMT) and the Study Leadership Team (SLT), across the internal matrix and a broad range of external experts.
* Make significant contributions to global regulatory submissions/files, including briefing documents, presentations, and responses to regulatory questions.
* Evaluate specific business development activities, including due diligence, and contribute to the implementation and embedding of strategic/organizational initiatives in Clinical Development.
* Stay abreast of advancements in therapeutic area research, clinical trial methodologies, competitive environment, and regulatory space to maintain GSK’s competitive edge.
Additional Responsibilities
* Demonstrate flexibility and adaptability in changing environments and ability to analyze incomplete information, identify potential risks and implications, and make informed decisions.
* Demonstrate enterprise mindset with effective collaboration across the matrix and integrate cross‑functional knowledge into decision‑making processes.
* Embrace challenge as an opportunity, proactively generating ideas for innovative improvement and promoting an environment for others to be creative.
* Manage conflicts effectively and independently, negotiating mutually acceptable solutions.
* Analyze, interpret and critically evaluate data, information and digital content to anticipate obstacles and identify potential solutions.
* Consistently achieve desired outcomes through strong influencing skills, building trust, tailoring communications, and using persuasive arguments to gain support.
Basic Qualifications
* Medical Degree.
* Completion of formal postgraduate clinical training (e.g., Internal Medicine, Primary Care / Family Medicine), leading to board eligibility or certification.
* Experience in clinical research and drug development, including experience relevant to respiratory diseases.
Preferred Qualifications
* Medical degree with formal specialty training and board qualification/registration in Pulmonary Medicine, Pulmonary & Critical Care, or Respiratory Medicine.
* Experience working in the global pharmaceutical or biotechnology industry within respiratory diseases.
* Experience leading global clinical trials and contributing to NDA, BLA, or MAA submissions.
* Experience in late‑stage respiratory drug development, including design, initiation, execution, and closure of Phase 2 and Phase 3 clinical trials.
Salary and Benefits
• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $222,750 to $371,250.
The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. This position offers an annual bonus and eligibility to participate in our share‑based long‑term incentive program which is dependent on the level of the role.
Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.
Equal Opportunity
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
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