This post is for a full-time Research Assistant in the laboratory of Professor Steve Jackson ( ) based in the internationally renowned Cancer Research UK Cambridge Institute, located on the Cambridge Biomedical Campus, Cambridge, UK.
Responsibilities
* The postholder will work alongside experienced postdoctoral research associates to assist with several on-going projects in the lab, exploring the cellular mechanisms of DNA-damage responses and investigating how sensitivity and resistance arise in different cancer cells with different genetic backgrounds when exposed to radioligand treatments and combination therapies involving clinically relevant drugs.
* The research assistant will be required to take on other responsibilities, including preparation of reagents, maintenance of lab stocks and assisting in the day-to-day running of the laboratory.
* The postholder will assist with high-throughput CRISPR-Cas9 screens to explore sensitivity/resistance mechanisms in defined genetic backgrounds, followed by validation and ensuing mechanistic studies.
Qualifications
* Experience in CRISPR genome editing and/or CRISPR genetic screens is desirable, as well as a strong background in cell and molecular biology techniques, tissue culture, and stable cell line generation.
* The successful candidate should show initiative and independent thinking, possess excellent communication skills and the ability to work independently and as a part of a vibrant and diverse team.
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