Research Associate - A Versatile Biocatalytic Platform for Scalable Therapeutic Oligonucleotide Manufacturing, Manchester
Client:
The University of Manchester
Location:
Manchester, United Kingdom
Job Category:
Other
EU work permit required:
Yes
Job Reference:
730dc0004e76
Job Views:
6
Posted:
02.05.2025
Expiry Date:
16.06.2025
Job Description:
Research Focus: Development of a versatile biocatalytic platform for scalable therapeutic oligonucleotide manufacturing.
Position: Postdoctoral Research Associate with experience in directed evolution, biocatalysis, biochemistry, or related disciplines.
Objective: To develop and optimize biocatalytic methods for therapeutic oligonucleotide synthesis.
Location: Manchester Institute of Biotechnology (MIB), supervised by Dr. Sarah Lovelock, with collaboration with industry partners such as AstraZeneca, Novartis, CPI, Novo Nordisk, and BioMarin.
Background: Therapeutic oligonucleotides target mRNA to modulate protein production and represent a promising drug modality. Current chemical synthesis methods face scalability limitations.
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