The (the Franklin) is a technology institute established by the UK Government as a unique centre committed to advancing tools that are needed to transform healthcare in the future.
The Institute brings together researchers in life and physical sciences, and engineering, to develop a spectrum of tools which we will use to image, interpret and intervene in biological systems. These insights will speed up the discovery of new medicines, help find new diagnostics and contribute to a deeper understanding of human health and disease. Our Science Strategy seeks to focus the Franklin’s research and unite our researchers around our Technology Innovation Challenges and Life Science Challenges. For more information on the Franklin’s Challenges .
The Role
We are seeking a highly motivated Research Assistant to support cutting-edge research in cell-cell interaction in epithelia. The role will focus on the development and genetic modification of human gut organoid and cell models, including the generation of fluorescently tagged proteins and disease-relevant phenotypes. The role will involve apply molecular biology techniques including DNA cloning, qPCR, and sequencing, CRISPR/Cas9 genome editing, advanced 2D and 3D cell culture, and fluorescence imaging techniques including super resolution. The post-holder will handle human tissue samples in compliance with HTA regulations and prepare growth factors for organoid maintenance.
The successful candidate will support a collaborative, multidisciplinary research environment.
Key Responsibilities
As a Research Assistant at the Franklin, you will become an integral part of the research team, supporting the work of scientists, by ensuring the smooth running of the labs. You will manage technologies and reagents and provide services to support the work of students and scientists of all levels. You may also be asked to undertake well defined experimental protocols in a supervised fashion.
You will also:
1. *Work with students and teams of researchers/technologists around established projects.
2. *Manage day to day running of the facilities and ensure that specific activities within the lab perform well.
3. *Keep meticulous records, ensuring compliance of lab processes, ordering and stocking, maintenance and operations.
4. *Support use of facilities, production of samples or performing aspects on behalf of researchers, with due consideration to health and safety.
5. *Be supervised by Lab Managers/Scientists.
6. *Be involved in scientific portfolio, including publications, projects or conferences.