We are seeking
a Research Assistant to join the Laboratory of Molecular Neurodegeneration in the Department of Physiology, Anatomy and Genetics, University of Oxford. The ideal candidate will be a highly motivated cell biologist with experience in stem cell culture, neuronal differentiation, and phenotypic assays. Strong skills in neurobiology, cell imaging, and molecular techniques are essential, along with the ability to work collaboratively. In this role, you will be responsible for undertaking a range of cell culture activity working with patient primary fibroblasts, iPSC lines and iPSC-derived neurons and glia, performing analysis of Parkinson’s molecular and cellular biology and correlating read-outs of cell and molecular biology with detailed clinical phenotypes to contribute to our understanding of Parkinson’s disease. This post is funded by the Oxford/GSK Institute of Cellular & Computational Medicine (IMCM) and available immediately until September 2027. Key responsibilities:
1. Undertake maintenance culture of fibroblast and iPSC lines, and differentiation of iPSC lines into dopamine neurons and glia
2. Contribute to wider project planning, including ideas for new research projects
3. Determine the most appropriate methodologies to test hypotheses, and identify suitable alternatives if technical problems arise
4. Select, follow, and adapt experimental protocols
5. Gather, analyse, and present scientific data from a variety of sources
6. Contribute to scientific reports and journal articles and the presentation of data/papers at conferences
7. Manage own research and administrative activities, within guidelines provided by senior colleagues
8. Collaborate effectively with other team members to achieve collective goals
Selection criteria:
9. Hold or be near to completion of BSc or MSc degree in neuroscience or cell/molecular biology or equivalent.
10. Have experience in neuronal/glial cell culture, preferably in human pluripotent stem cells
11. Have experience in setting up cellular assays, including image-based experiments
12. Have knowledge of neurodegenerative diseases, such as Parkinson’s
13. Be highly motivated, with the capacity to think creatively and work across teams
14. Show commitment to engaging with, and promoting awareness of, equality, diversity and inclusion and embedding these into your work.
What we offer: Your wellbeing at work matters, so we offer a range of family friendly and financial benefits including:
15. An excellent contributory pension scheme
16. 38 days annual leave
17. A comprehensive range of childcare services
18. Family leave schemes
19. Cycle and electric car loan schemes
20. Employee Assistance Programme
21. Membership to a variety of social and sports clubs
22. Discounted bus travel and Season Ticket travel loans