We are seeking a Skin Bioassay Senior Scientist to join a growing CRO environment developing advanced in vitro skin models and bioassays for both pharmaceutical and cosmetic applications.
This role is part of a strategic expansion of in-house skin capabilities, supporting both ongoing projects and the development of new model systems. You will play a key role in generating high-quality datasets, developing human-relevant skin models, and delivering impactful assay results for clients.
Working within a collaborative, fast‑paced laboratory environment, you will contribute to the development of next‑generation skin models, including reconstructed and full‑thickness systems, while supporting a broad range of client‑driven and internal projects.
Responsibilities
* Develop and optimise in vitro skin models, including:
o Full‑thickness or full‑skin equivalent systems
o Contribute to the evolution of increasingly complex, physiologically relevant models
Assay Development & Delivery
* Design and execute cosmetic and skin‑related bioassays, including:
o Cell proliferation and viability assays
o Cytokine release and inflammatory markers
o Barrier function and sensitivity assessments
* Analyse and interpret experimental data, ensuring generation of robust, client‑ready datasets
* Apply a range of techniques including:
o ELISA and immunoassays
o qPCR and molecular biology workflows
o Plate‑based assay readouts
* Use imaging and histology‑based approaches to assess skin structure and function
Applied Skin Science & Testing
* Evaluate cosmetic formulations and active compounds
* Ageing processes and protective effects
* UV response (using in‑house UV systems)
* Key skin proteins such as keratin and structural markers
Project Delivery & Lab Operations
* Deliver experimental work in line with project timelines and client expectations
* Prepare SOPs, reports, and technical documentation
* Troubleshoot experiments and contribute to continuous improvement initiatives
About You
You are a hands‑on scientist with experience in skin biology and in vitro model systems, comfortable working in a fast‑paced, applied research or CRO environment.
You’ll Bring
* Experience working with in vitro skin models (essential)
* Strong laboratory experience across cell‑based assays and bioassays
* Knowledge of ELISA, immunoassays, qPCR, and cell culture techniques
* A practical, delivery‑focused mindset with strong attention to detail
Highly Desirable
* Exposure to full‑skin equivalent or 3D skin models
* Experience in cosmetic testing, skin ageing, or UV response studies
* Background in CROs or applied commercial research
PhD candidates or those with 2–3 years of relevant industry experience are both encouraged to apply.
This is a great opportunity to join a growing organisation at a key stage, where you will not only deliver projects but also help shape the future direction of skin model development within the business.
#J-18808-Ljbffr