A leading, research-driven biopharmaceutical organisation is seeking an experienced Senior Scientist – In‑Vivo Pharmacology to join its Immunology Discovery team.
This is an exciting opportunity to contribute to the discovery and early development of innovative small molecules and biologics targeting immune‑mediated inflammatory diseases. The role is hands‑on and delivery‑focused, playing a critical part in generating high‑quality in vivo data to support key project decisions.
Responsibilities
As a Senior Scientist within the In Vivo Pharmacology group, you will :
* Design, plan, and execute in vivo studies to support target identification, validation, and translational pharmacology.
* Apply strong expertise in immunology models, ensuring robust experimental design and scientific rigor.
* Generate, analyse, and interpret complex in vivo datasets to drive project progression.
* Support the establishment, optimisation, and validation of in vivo models.
* Oversee outsourced studies with CRO partners where required.
* Contribute to cross‑functional project teams, providing scientific insight to inform decision‑making.
* Ensure full compliance with regulatory, ethical, and animal welfare standards.
* Maintain clear documentation and contribute to reports, study summaries, and presentations.
You will work closely with internal project teams, matrix functions, and external collaborators in a highly collaborative research environment.
The ideal candidate will have
* A PhD (or equivalent) in Pharmacology, Immunology, or a related discipline.
* Postdoctoral or industry experience within drug discovery.
* Strong hands‑on expertise in in vivo pharmacology, particularly within immunology and inflammatory disease models.
* Demonstrated ability to design rigorous in vivo experiments and interpret complex biological data.
* Experience with in vivo cell depletion models (desirable).
* A Home Office Project Licence (or eligibility to obtain one).
* A pragmatic, delivery‑focused approach with high attention to data quality and scientific standards.
* The ability to work independently while contributing effectively within a collaborative team.
Keywords: In‑vivo, Pharmacology, Models, Immunology, Pharmacology, inflammatory, immune, Home office licence, PIL, Target identification, validation, translational pharmacology, Slough, Windlesham, London, Oxford, Cabridge, Reading, VRS9359DT
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