Abcam is seeking a Senior Scientist – Antibody Data & Epitope Strategy to join the Danaher Affinity Reagents Autonomous Laboratory (DARAL) in Cambridge, UK. This lab‑based position reports to the Director of Production and focuses on experimental antibody research and data generation with an emphasis on sequencing, repertoire diversity, and epitope‑level insight.
In This Role, You Will Have The Opportunity To
* Design and execute experiments to generate antibody sequence, repertoire, and epitope‑level data
* Integrate sequencing outputs with binding and functional data to understand antibody diversity and convergence
* Develop experimental strategies that link sequence space to biological behaviour across hard targets
* Use data‑driven insight to inform antibody format choice, target prioritisation, and progression decisions within DARAL
* Partner with engineering, automation, and data teams to ensure sequencing‑enabled experiments are scalable and reusable
The Essential Requirements Of The Job Include
* PhD (or equivalent) in a life sciences discipline, with 5+ years’ experience in antibody discovery, protein science, or related experimental fields
* Strong understanding of antibody sequence–structure–function relationships, including epitope recognition and biological context
* Hands‑on experience generating or analysing antibody sequence or repertoire data
* Experience with experimental approaches to epitope characterisation (e.g. competition assays, mutagenesis, domain mapping, or binning strategies)
* Excellent communication skills, with the ability to explain scientific trade‑offs and priorities to diverse stakeholders
It would be a plus if you also possess previous experience in
* Antibody repertoire sequencing, NGS‑enabled discovery, or diversity analysis
* Alternative antibody formats (e.g. VHHs, scFvs, engineered libraries)
* Relating sequence and epitope diversity to downstream reagent performance
* Working on hard‑to‑drug or historically challenging targets (e.g. membrane proteins)
* Supporting higher‑throughput or automation‑ready antibody discovery workflows
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