Job Summary
Salary: Grade 7 (£41,064 - £48,822 p.a.)
This role will be based on the university campus. We are open to discussing flexible working arrangements.
We are looking for a structural mass spectrometry (MS) scientist within the Faculty of Biological Sciences and the Astbury Centre for Structural Molecular Biology to work on multiple projects as a structural mass spectrometry expert in hydrogen‑deuterium exchange-MS, native MS, chemical crosslinking-MS, and various top‑down and bottom‑up proteomics approaches. The role involves expert guidance, training, and advice in sample preparation, optimisation, method development, data acquisition, and interpretation.
Responsibilities
* Support the range of mass spectrometry modalities available in the facility, including hydrogen‑deuterium exchange, native MS, intact protein mass measurement, proteomics, and metabolomics.
* Provide an efficient analytical service for users, performing analyses.
* Give advice on sample preparation, experimental design, and data interpretation.
* Actively establish internal and external links with research groups and industrial partners.
* Develop new techniques for biomolecular analysis.
* Write technical summaries and project reports.
* Maintain mass spectrometry and chromatography equipment in good working order.
* Perform other general laboratory duties.
* Provide expert guidance, training and advice on method development, data acquisition and interpretation.
Qualifications
* PhD in chemistry, biochemistry, analytical science, structural molecular biology or a related discipline (or close to completion).
* Experience with at least one structural MS method.
* Passion for studying biological mechanisms relevant to human disease.
* Excellent verbal and written communication and interpersonal skills.
* Ability to work closely, interactively and collaboratively with the facility team, the wider MS community and external partners.
Additional Information
Vacancy may be suitable for sponsorship under the Skilled Worker visa route. First‑time applicants may need to qualify for salary concessions. For more information, visit www.gov.uk/skilled-worker-visa.
For research and academic posts, eligibility under the Global Talent visa will be considered. For more information, visit www.gov.uk/global-talent.
Contact
Dr Brian Jackson, Head of Research Facilities
Email: B.R.Jackson@leeds.ac.uk
Dr Anton Calabrese, Associate Professor in Biological Mass Spectrometry
Email: A.Calabrese@leeds.ac.uk
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