Overview
Help build the worlds first automated "airlock" for health research environments.
At UK Biobank, we are developing new technologies that will help researchers securely work with some of the worlds richest biomedical datasets. This role sits within a team building what is believed to be the worlds first automated output checking system for trusted research environments using AI and cloud-native technologies to help ensure researchers can only export files regarded as safe. It is a genuinely greenfield engineering challenge, combining AI-driven approaches, secure cloud-native architecture, and modern full-stack development to support global health research.
You will lead the development, integration, and delivery of the UK Biobank Automated Output Checking System, helping shape a platform that supports secure research at a global scale. Working closely with architects, researchers, vendors, and internal engineering teams, you will design and build scalable integrations across research platforms and cloud-native services. This role combines hands‑on engineering, technical leadership, and modern platform design, requiring someone who can comfortably work across backend services, frontend applications, infrastructure, APIs, and cloud environments. The solution applies AI techniques, follows cloud‑native principles, and is being built from the ground up, giving you the opportunity to influence both architecture and technical direction.
Responsibilities
* Ensure integration patterns align with enterprise architecture principles, including event‑driven, API‑first, and microservices‑based approaches.
* Design and develop scalable, secure, cost‑efficient and maintainable full‑stack applications using Python (backend) and TypeScript (frontend), including relational and non‑relational database management systems on AWS.
* Develop responsive and accessible user interfaces using modern frontend frameworks such as React with TypeScript.
* Develop and manage infrastructure using Infrastructure as Code (Terraform), ensuring reproducible and auditable environments. Develop CI/CD pipelines to enable continuous integration, testing, and deployment.
* Ensure systems are designed with observability, logging, and monitoring to support operational excellence.
Qualifications
* Full‑stack software development experience within enterprise environments.
* Backend development using Python frameworks such as FastAPI, Flask, or similar.
* Frontend development experience using TypeScript and modern frameworks such as React or Vue.
* Experience with AWS services such as IAM, S3, Lambda, ECS/EKS, API Gateway, and Step Functions.
* Knowledge of microservices architecture and distributed systems.
* Experience designing and consuming secure APIs with CI/CD pipelines and DevOps tooling.
Location & Hours
Working hours are 35 hours per week, Monday to Friday, with some flexibility, 2 days onsite with hybrid working available. Located in Greater Manchester (initially based in Stockport with a move to Manchester Science Park mid to late 2026).
Our Diversity Commitment
We actively welcome applications from people with disabilities, long‑term health conditions, neurodivergent candidates, and those with diverse thinking styles. We are committed to making reasonable adjustments throughout our recruitment process and in the workplace so that everyone can perform at their best. If you require any adjustments during the recruitment process, please contact Tommy Wilson so we can support you.
Benefits
* 26 Days Annual Leave plus Bank Holidays
* Holiday Buy Scheme
* Birthday Leave
* USS Pension Scheme
* Healthcare Cash Plan
* Enhanced Family Leave
* Cycle to Work Scheme
* Season Ticket Loan
* Professional Subscriptions
* £500 annual training budget
* Free On‑Site Gym
* Subsidised Canteen Lunches
* Free Car Parking
* Employee Discounts Portal
* Employee Assistance Programme
* Annual Flu Vaccination
* Life Assurance Cover
About UK Biobank
UK Biobank is a large‑scale biomedical database and research resource containing in‑depth genetic and health information from half a million UK participants. The database, the largest and most comprehensive of its kind in the world, is anonymised and made widely accessible by UK Biobank to global researchers who use it to find new scientific discoveries about common and life‑threatening diseases such as cancer, heart disease and stroke. UK Biobank is an innovative organisation with over 350 staff across four sites in the UK that fosters an engaging environment and supports the development of our staff. Our dedicated teams work alongside the worlds leading biomedical scientists in our joint mission to improve public health.
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