S alary: £27,319.00 - £29,588.00 per annum Newcastle University is a great place to work, with excellent benefits. We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you. Closing Date: 03 March 2026 The Role The role requires a talented Research Technician to work on a Rosetrees Trust funded project investigating the role of Immunosuppressive Macrophages in Hepatocellular Carcinoma (HCC). The post will join a wider community of technical professionals within the Faculty of Medicine overseen by the technical manager. The role will be is based in the Newcastle Fibrosis Research Group. The post will join the wider research group working on Immunosuppressive Macrophages in Hepatocellular Carcinoma (HCC) which is the 3rd major cause of cancer related deaths. This research project will use complex human and mouse (including humanised mice) ex-vivo and in vivo pre-clinical models of HCC to explore if manipulating the biology of immunosuppressive macrophages in HCC and inhibiting their ability to infiltrate tumours enhances immunotherapy in metabolic-associated steatohepatitis (MASH)-HCC. This post is full time, for a fixed term period until 31 October 2028. Applicants who wish to work less than full time may be considered. For informal inquiries, contact Professor Fiona Oakley ( fiona.oakley@newcastle.ac.uk ) or Professor Derek Mann ( derek.mann@newcastle.ac.uk ). Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/ Key Accountabilities To be responsible for day-to-day management and support of experimental work involving human and mouse tissue/cells To gain familiarity in the relevant human and mouse models of HCC to conduct relevant experiments (initially under supervision, and then independently) To keep accurate, secure, detailed and up to date records of all work carried out under the guidance of research staff Liaise with suppliers and manufacturers to resolve problems and investigate replacement options Assist with the completion and updating of a wide range of safety paperwork Oversee compliance tasks ensuring timely completion and maintenance of appropriate records Maintain broad and up to date health and safety knowledge providing support/advice to others Schedule, prioritize and monitor work and performance in line with demands and deadlines Attend research seminars and other departmental meetings as required Contribute to the presentation of results to the academic leads and to the group more widely. Hold delegated responsibility from the academic/technical lead for the planning, operation, and supervision of a variety of laboratory spaces Work collaboratively with the other areas to ensure efficiency and elimination of duplicated effort Be a key contributor to service development, delivery and planning Contribute and support change Monitor resource usage and stores operations Create, update and implement procedures to deliver an aligned, efficient and effective service Provide a broad range of skilled research/teaching support Prepare and manufacture a range of specimens/samples with limited direction Design, develop and deliver inductions, demonstrations and training covering a broad range of activities (not limited to techniques and equipment) Assist managers with the identification of training and development needs Develop a broad knowledge and skills base, sharing with others Out of hours work if required Any other duties within the scope and general nature of the grade which may be required The Person (Essential) Knowledge, Skills and Experience Thorough working knowledge of Health and Safety procedures, and experience of safe waste management within a workshop/laboratory environment Demonstrable work experience in a relevant technical laboratory role eg: experience of PCR, ELISAs, sterile cell culture, histology, immunohistochemistry Excellent team working skills Demonstrates technical and problem solving capability Demonstrates good organising ability to meet deadlines with a positive and proactive approach to duties and attention to detail Contribute to design and specification of teaching/research activities (Desirable) Flow cytometry experience (desirable) Ability to adapt to changes in teaching/research priorities Attributes and Behaviour Passionate about cancer research and/or liver diseases Eagerness to develop new skills Excellent oral and written communication skills Good interpersonal skills to interface with staff Attention to detail to ensure accuracy and precision Work in a collaborative and flexible way To exhibit University and Faculty values and principles Qualifications BTEC HNC/HND or equivalent in a biosciences subject or related field or equivalent experience in this area A BSc in a related Biosciences field (Desirable) An MSc or MRes in Cancer Research or Biosciences related field (Desirable) Professional registration with an accredited professional body (including HEA) or working towards this on appointment (Desirable) Success Factors Team-working (Self) Co-operative Respects the expertise and contribution of others even if own opinion is different Shares relevant and useful information with others Keeps other team members up to date with progress Gets involved with team tasks Willing to help others and share workloads Supportive of team decisions Asks others’ opinion Encourages others to get involved Talks about other team members in a positive way Respects the value that different views bring to the team Planning and organising (Self) Planning and managing own work Works in a planned and structured way Uses own and others’ time effectively Sets own priorities in conjunction with team and area objectives Plans workload and tasks in a systematic way Ensures that all activities are completed on time Uses systems and tools to ensure records and audit trails are clear and up to date Keeps work systems up to date, neat and tidy Ensures that others know how process and systems work Delivering services (Self) Getting the job done well Sees others departments and colleagues as “customers” and follows through on their enquiries and requests Keeps fellow team members up to date with progress Co-operates with others in achieving targets Takes responsibility for achieving own targets Has a positive attitude for doing things better Looks for ways to make immediate improvements (quick wins) Pays attention to detail Strives to deliver high quality results Is enthusiastic in getting the job done on time Embracing Change (Self) Making improvements in your own role Comes forward with new ideas and concepts Anticipates change and prepares for it Accepts change and “runs” with it Willing to experiment, enterprising in approach Builds on others’ ideas and suggestions Willing to change ways and policies in light of new information Communicating (Self) Clear communicator Is factually correct and gives consistent verbal and non verbal messages Clear and concise; gets the message across to others Chooses communication tools appropriately e.g. selective use of emails and other channels of communicationTailors content of communication to the audience, changing style, tone and format appropriately Uses face to face communication regularly; team meetings, one to ones, informal discussions/chats, briefing sessions etc Can hold attention of others using appropriate techniques; questioning, rhetorical questions, changing tone and pace of voice and animated style Newcastle University is a global University where everyone is treated with dignity and respect. As a University of Sanctuary, we aim to provide a welcoming place of safety for all, offering opportunities to people fleeing violence and persecution. We are committed to being a fully inclusive university which actively recruits, supports and retains colleagues from all sectors of society. We value diversity as well as celebrate, support and thrive on the contributions of all of our employees and the communities they represent. We are proud to be an equal opportunities employer and encourage applications from individuals who can complement our existing teams, we believe that success is built on having teams whose backgrounds and experiences reflect the diversity of our university and student population. At Newcastle University we hold a Gold Athena Swan award in recognition of our good employment practices for the advancement of gender equality. We also hold a Race Equality Charter Bronze award in recognition of our work towards tackling race inequality in higher education REC. We are a Disability Confident employer and will offer an interview to disabled applicants who meet the essential criteria for the role as part of the offer and interview scheme. In addition, we are a member of the Euraxess initiative supporting researchers in Europe. Requisition ID: 29057