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Advanced therapies production scientist/research associate - strand, london, wc2r 2ls

London
Kings College London
Research associate
Posted: 11 June
Offer description

Advanced Therapies Production Scientist/Research Associate - Strand, London, WC2R 2LSAbout UsKing’s College London and its partner NHS Trusts – King’s College Hospital and Guy’s & St Thomas’ Hospital together have one of the largest chimeric antigen receptor T (CAR-T) cell programmes in the UK with licensed and experimental CAR-T products being administered for patients with B-cell leukaemias, lymphomas, multiple myeloma, solid tumours and autoimmune disease. About The RoleThis role is to lead the GMP manufacturing of CAR-T cells for a Cancer Research UK funded, first-in-human, anti-CD19 CAR-T study for B-cell lymphomas due to open at King’s College Hospital in 2026. The postholder will lead a team of CAR-T cell production scientists and technicians based at King’s Cell Therapy Unit (CTU) in Denmark Hill and work closely with the pre-clinical, process development and Haematology department clinical teams. King’s CTU offers GMP manufacturing facilities for cell and gene therapy products including lenti/retroviral vectors, hepatocytes, islet cells, mesenchymal stromal cells and CAR-T cells. The postholder will have a strong background in GMP manufacturing of advanced therapy investigational medicinal products (ATiMPs), be proficient in flow cytometry, have prior experience with clinical trials and an in-depth knowledge of immunology and CAR-T cell biology. The individual may also be required to support GMP manufacturing of other ATiMPs at King’s CTU and at Guy’s & St Thomas’ Hospital GMP facility. This is an excellent opportunity for an experienced production scientist to join a rapidly expanding academic CAR-T programme at King’s Health Partners and contribute to innovative research enabling patients with refractory cancers to be treated with potentially transformative CAR-T therapy products. This is a full time post (35 Hours per week), and you will be offered a fixed term contract until 20/07/2027 with the likelihood of a 3 year extension for delivering a 5 year clinical study.

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