We are seeking
to appoint a Postdoctoral Researcher to join a new collaboration between Associate Professor Katherine Bull’s renal pathology group and GlaxoSmithKline, within the Oxford-GSK Institute for Molecular and Computational Medicine (IMCM). You will test GSK assets and targets in established models of podocyte and mesangial cell pathology relevant to glomerular diseases. You will establish and validate microfluidic co-culture systems using human glomerular cells and benchmark these platforms against human kidney multi-omic and spatial datasets. These systems will be further developed to model immune-mediated kidney injury. Quantitative and reproducible read-outs from these assays will be correlated with human kidney ‘omics data to evaluate the impact of pathway modulation, ultimately enhancing the clinical relevance of experimental findings and supporting the development of novel therapies.